Heterogeneity of cytochrome P-450 distribution in the hepatic lobule revealed by carbon tetrachloride

1979 ◽  
Vol 87 (4) ◽  
pp. 374-376 ◽  
Author(s):  
V. M. Faktor ◽  
I. V. Uryvaeva ◽  
V. E. Kagan
Keyword(s):  
Carbon Tetrachloride ◽  
Hepatic Lobule ◽  
Cytochrome P 450

scholarly journals Hepatoprotective Action of Phytopreparation from Limonium gmelinii

2017 ◽  
Vol 4 (1) ◽  
pp. 67
Author(s):  
G.E. Zhusupova ◽  
T.M. Shalakhmetova ◽  
Sh.N. Askarova
Keyword(s):  
Chronic Hepatitis ◽  
Carbon Tetrachloride ◽  
Inflammatory Cell ◽  
Simultaneous Administration ◽  
Hepatic Parenchyma ◽  
Hepatic Lobule ◽  
Cadmium Sulfate ◽  
Chronic Intoxication ◽  
Postnecrotic Cirrhosis ◽  
Limonium Gmelinii

<em></em>Effects of phytopreparation from a plant of <em>Limonium gmelinii</em> were studied on livers of white breedless rats at chronic impact of cadmium sulfate and carbon tetrachloride. It was established the administration of cadmium sulfate during six months caused chronic hepatitis, while the simultaneous administration of preparation from <em>Limonium gmelinii</em> and cadmium sulfate did not result of destructive changes in a liver. Chronic intoxication of the animals by carbon tetrachloride during six months caused progressive postnecrotic cirrhosis. The simultaneous administration of phytopreparation and carbon tetrachloride caused postnecrotic fibrosis in the central part of hepatic lobule only. Not only dystrophic and necrobiotic processes also numerous inflammatory cell infiltrates were observed in hepatic parenchyma of animals which were treated by cadmium sulfate and carbon tetrachloride, while it was not observed at animals which were medicated with phytopreparation. Thus, on the basis of the data was concluded about hepatoprotective action of phytopreparation from<em> Limonium gmelinii</em>.

Formation of electrophilic chlorine from carbon tetrachloride—involvement of cytochrome P-450

1983 ◽  
Vol 32 (15) ◽  
pp. 2357-2359 ◽  
Author(s):  
Bruce A. Mico ◽  
Richard V. Branchflower ◽  
Lance R. Pohl
Keyword(s):  
Carbon Tetrachloride ◽  
Cytochrome P 450

Early destruction of cytochrome P-450 in testis of carbon tetrachloride poisoned rats

Toxicology ◽  
1978 ◽  
Vol 10 ◽  
pp. 39-44 ◽  
Author(s):  
Edith G.D de Toranzo ◽  
Maria C Villarruel ◽  
Jose A Castro
Keyword(s):  
Carbon Tetrachloride ◽  
Cytochrome P 450

Age-related changes in distribution of cytochrome P-450 in the hepatic lobule of the rat

1990 ◽  
Vol 11 (1) ◽  
pp. 43-52
Author(s):  
Takeo Machida ◽  
Masaya Miyatake ◽  
C.F.A. van Bezooijen
Keyword(s):  
Hepatic Lobule ◽  
Age Related ◽  
Cytochrome P 450 ◽  
Age Related Changes

Immunofluorescence of phenobarbital inducible cytochrome P-450 in the hepatic lobule of normal and phenobarbital-treated rats

Hepatology ◽  
1982 ◽  
Vol 2 (6) ◽  
pp. 849-855 ◽  
Author(s):  
Kunihiko Ohnishi ◽  
Akihiko Mishima ◽  
Kunio Okuda
Keyword(s):  
Hepatic Lobule ◽  
Cytochrome P 450
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