Effect of repeated percutaneous applications of heavy pyrolysis resin on the cytochrome P-450 level and glutathione transferase activity in rat liver microsomes and cytosol: Correlation with toxic action of pyrolysis resin on internal organs

1990 ◽  
Vol 110 (4) ◽  
pp. 1337-1340
Author(s):  
M. N. Kravchenko ◽  
A. S. Loginov ◽  
L. P. Petrova ◽  
L. Kh. Ausheva ◽  
�. A. Bendikov
Keyword(s):  
Rat Liver ◽  
Glutathione Transferase ◽  
Liver Microsomes ◽  
Toxic Action ◽  
Transferase Activity ◽  
Rat Liver Microsomes ◽  
Internal Organs ◽  
Cytochrome P 450 ◽  
Heavy Pyrolysis Resin

Interlaboratory comparison of total cytochrome P-450 and protein determinations in rat liver microsomes

1987 ◽  
Vol 61 (1) ◽  
pp. 27-33 ◽  
Author(s):  
Alphons A. J. J. L. Rutten ◽  
Hein E. Falke ◽  
Jan F. Catsburg ◽  
Randy Topp ◽  
Bas J. Blaauboer ◽  
...  
Keyword(s):  
Rat Liver ◽  
Interlaboratory Comparison ◽  
Liver Microsomes ◽  
Rat Liver Microsomes ◽  
Cytochrome P 450

scholarly journals Reconstitution of purified Wistar rat liver bilirubin UDP-glucuronyltransferase into Gunn-rat liver microsomes

1982 ◽  
Vol 201 (3) ◽  
pp. 653-656 ◽  
Author(s):  
B Burchell
Keyword(s):  
Enzyme Activity ◽  
Rat Liver ◽  
Specific Activity ◽  
Liver Microsomes ◽  
Wistar Rat ◽  
Transferase Activity ◽  
Rat Liver Microsomes ◽  
Phosphatidylcholine Liposomes ◽  
Gunn Rat ◽  
Rigid Environment

1. Reconstitution of purified bilirubin UDP-glucuronyltransferase from Wistar-rat liver into Gunn-rat liver microsomes provides a better environment than phosphatidylcholine liposomes, such that the final specific activity of the Wistar-rat liver enzyme was increased up to 85 units/mg of protein. 2. Gunn- and Wistar-rat liver microsomes were equally effective for reconstitution of the purified enzyme. 3. The transferase activity does not appear to be fully expressed in the more rigid environment of foetal Wistar-rat liver microsomes. 4. These reconstitution experiments reveal a final specific activity for the purified bilirubin UDP-glucuronyltransferase consistent with the capacity of the whole rat liver to glucuronidate bilirubin and indicate that the absence of this enzyme activity in Gunn-rat liver microsomes is not due to an abnormal microenvironment.

Pituitary regulation of cytochrome P-450-mediated metabolism of steroids and xenobiotics in rat liver microsomes

1986 ◽  
Vol 7 (4) ◽  
pp. 575-582 ◽  
Author(s):  
Agneta Blanck ◽  
Anders Åström ◽  
Tiiu Hansson ◽  
Joseph W. De Pierre ◽  
Jan-Åke Gustafsson
Keyword(s):  
Rat Liver ◽  
Liver Microsomes ◽  
Rat Liver Microsomes ◽  
Cytochrome P 450
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