Histamine H2-receptor blocking activity of ranitidine and lamtidine analogues containing aminomethyl-substituted aliphatic systems

M. Orsetti

doi:10.1007/bf01965034

Histamine H2-receptor blocking activity of ranitidine and lamtidine analogues containing aminomethyl-substituted aliphatic systems

Agents and Actions ◽

10.1007/bf01965034 ◽

1988 ◽

Vol 25 (3-4) ◽

pp. 291-295 ◽

Cited By ~ 2

Author(s):

M. Orsetti

Keyword(s):

Histamine H2 Receptor ◽

Receptor Blocking ◽

H2 Receptor ◽

Blocking Activity

Histamine H2-receptor blocking activity of ranitidine analogues containing 3-amino-4-alkylaminofurazan moieties

Pharmacological Research ◽

10.1016/1043-6618(89)90140-0 ◽

1989 ◽

Vol 21 (1) ◽

pp. 115-116

Author(s):

M ORSETTI ◽

L OGGERO ◽

G SORBA

Keyword(s):

Histamine H2 Receptor ◽

Receptor Blocking ◽

H2 Receptor ◽

Blocking Activity

Anti-ulcer compound from Voacanga africana with possible histamine H2 receptor blocking activity

Phytomedicine ◽

10.1016/s0944-7113(00)80037-9 ◽

2000 ◽

Vol 7 (6) ◽

pp. 509-515 ◽

Cited By ~ 14

Author(s):

P.V. Tan ◽

B. Nyasse

Keyword(s):

Histamine H2 Receptor ◽

Receptor Blocking ◽

H2 Receptor ◽

Blocking Activity

A relatively specific and quantitative assay for histamine H2-receptor blocking activity by determination of inhibiton of histamine-induced gastric acid secretion in the rat

European Journal of Pharmacology ◽

10.1016/0014-2999(78)90201-7 ◽

1978 ◽

Vol 52 (2) ◽

pp. 153-159 ◽

Cited By ~ 1

Author(s):

Luis E. Borella ◽

Wilbur Lippmann

Keyword(s):

Acid Secretion ◽

Gastric Acid Secretion ◽

Gastric Acid ◽

Quantitative Assay ◽

Histamine H2 Receptor ◽

Receptor Blocking ◽

H2 Receptor ◽

Blocking Activity

New ranitidine analogues containing the 2-aminobenzimidazole moiety:in vivo andin vitro histamine H2-receptor blocking activity

Agents and Actions ◽

10.1007/bf01968087 ◽

1988 ◽

Vol 24 (1-2) ◽

pp. 109-113 ◽

Cited By ~ 3

Author(s):

M. Orsetti ◽

L. Oggero

Keyword(s):

Histamine H2 Receptor ◽

Receptor Blocking ◽

H2 Receptor ◽

Blocking Activity

α-Adrenoceptor blocking activity of histamine H2-receptor antagonists, ranitidine, cimetidine and metiamide, in isolated guinea pig heart

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)62691-0 ◽

1984 ◽

Vol 36 ◽

pp. 242

Author(s):

Kenichi Suzuki ◽

Kazuhiro Ohkubo ◽

Takeshi Otorii

Keyword(s):

Guinea Pig ◽

Receptor Antagonists ◽

H2 Receptor Antagonists ◽

Guinea Pig Heart ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Blocking Activity

Interaction of histamine H2-receptor blocking drugs with the noradrenergic system in rat brain and heart

European Journal of Pharmacology ◽

10.1016/0014-2999(80)90063-1 ◽

1980 ◽

Vol 68 (1) ◽

pp. 69-72 ◽

Cited By ~ 2

Author(s):

Jerzy Z. Zowak

Keyword(s):

Rat Brain ◽

Noradrenergic System ◽

Histamine H2 Receptor ◽

Receptor Blocking ◽

H2 Receptor

Selective and Competitive Histamine H2-Receptor Blocking Effect of Famotidine on the Blood Pressure Response in Dogs and the Acid Secretory Response in Rats

The Japanese Journal of Pharmacology ◽

10.1254/jjp.54.197 ◽

1990 ◽

Vol 54 (2) ◽

pp. 197-204 ◽

Cited By ~ 7

Author(s):

Keiji MIYATA ◽

Takeshi KAMATO ◽

Akira FUJIHARA ◽

Masaaki TAKEDA

Keyword(s):

Blood Pressure ◽

Blood Pressure Response ◽

Blocking Effect ◽

Pressure Response ◽

Secretory Response ◽

Histamine H2 Receptor ◽

Receptor Blocking ◽

H2 Receptor

Clinical pharmacology of a new histamine H2-receptor blocking agent, ranitidine

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)54432-8 ◽

1981 ◽

Vol 31 ◽

pp. 88

Author(s):

Akio Ebihara ◽

Taichi Oka ◽

Kazuji Tawara ◽

Kyoichi Ohashi ◽

Kazuoki Kondo ◽

...

Keyword(s):

Clinical Pharmacology ◽

Blocking Agent ◽

Histamine H2 Receptor ◽

Receptor Blocking ◽

H2 Receptor

Pharmacological basis for the induction of gastric carcinoid tumours in the rat by loxtidine, an unsurmountable histamine H2-receptor blocking drug

British Journal of Pharmacology ◽

10.1111/j.1476-5381.1985.tb11083.x ◽

1985 ◽

Vol 85 (4) ◽

pp. 843-847 ◽

Cited By ~ 64

Author(s):

R.T. Brittain ◽

D. Jack ◽

J.J. Reeves ◽

R. Stables

Keyword(s):

Gastric Carcinoid ◽

Blocking Drug ◽

Histamine H2 Receptor ◽

Receptor Blocking ◽

H2 Receptor ◽

Carcinoid Tumours ◽

Pharmacological Basis

Effects of two histamine H2-receptor blocking drugs on basal levels of gonadotrophins, prolactin, testosterone and oestradiol-17β during treatment of duodenal ulcer in male patients

Acta Endocrinologica ◽

10.1530/acta.0.0960564 ◽

1981 ◽

Vol 96 (4) ◽

pp. 564-568 ◽

Cited By ~ 43

Author(s):

N. R. Peden ◽

E. J. S. Boyd ◽

Margaret C. K. Browning ◽

J. H. B. Saunders ◽

K. G. Wormsley

Keyword(s):

Duodenal Ulcer ◽

Receptor Antagonist ◽

Serum Testosterone ◽

Histamine H2 Receptor ◽

Testosterone Treatment ◽

Receptor Blocking ◽

Blocking Activity ◽

Male Patients ◽

Ulcer Treatment ◽

Antiandrogenic Activity

Abstract. In a study of 51 male patients with duodenal ulcer, treatment with cimetidine was accompanied by an increase in basal levels of serum testosterone. Treatment with ranitidine, a new histamine H2-receptor antagonist, produced no such effect. It is concluded that cimetidine has antiandrogenic activity in man which is separate from the histamine H2-receptor blocking activity.