Long-term studies of visual field changes by means of computerized perimetry (Octopus 201) in eyes with glaucomatous field defects after normalization of the intra-ocular pressure

1989 ◽  
Vol 13 (1-2) ◽  
pp. 113-117 ◽  
Author(s):  
W. Leydhecker ◽  
E. Gramer
2011 ◽  
Vol 165 (1) ◽  
pp. 33-37 ◽  
Author(s):  
R Trifanescu ◽  
V Stavrinides ◽  
P Plaha ◽  
S Cudlip ◽  
J V Byrne ◽  
...  

ObjectiveTo clarify the outcome of all cases of Rathke's cleft cysts (RCC) treated surgically and followed up in Oxford during a long-term period.Subjects and methodsThe records of all patients with RCC seen in the Department of Endocrinology between January 1978 and June 2009 were reviewed.ResultsA total of 33 patients (20 females, median age 43 years) were identified. At presentation, major visual field defects were detected in 58% of patients and gonadotrophin, ACTH and TSH deficiency in 60, 36 and 36% of patients respectively. Desmopressin treatment was required in 18% of patients. Treatment consisted of cyst evacuation combined with or without biopsy/removal of the wall. Post-operatively, visual fields improved in 83% of patients with impairment, whereas there was no reversal of ACTH or TSH deficiency or of diabetes insipidus. All but one subject had imaging follow-up during a mean period of 48 months (range 2–267). Cyst relapse was detected in 22% of patients at a mean interval of 29 months (range 3–48 months); in 57% of them, the recurrence was symptomatic. Relapse-free rates were 88% at 24-months and 52% at 48-months follow-up. At last assessment, at least quadrantanopia was reported in 19% of patients, gonadotrophin, ACTH and TSH deficiency in 50, 42 and 47% of patients respectively. Desmopressin treatment was required in 39% of patients.ConclusionsIn this study of patients with RCC and long-term follow-up, we showed a considerable relapse rate necessitating long-term monitoring. Surgical intervention is of major importance for the restoration of visual field defects, but it does not improve endocrine morbidity, which in the long-term affects a substantial number of patients.


2011 ◽  
Vol 152 (2) ◽  
pp. 256-265.e1 ◽  
Author(s):  
Kyoko Ohno-Matsui ◽  
Noriaki Shimada ◽  
Kenjiro Yasuzumi ◽  
Kengo Hayashi ◽  
Takeshi Yoshida ◽  
...  

2017 ◽  
Vol 24 (10) ◽  
pp. 1527-1533
Author(s):  
Muhammad Khalid ◽  
Mehwish Aslam ◽  
Umer Farooq Raina ◽  
Khaleeq UZ Zaman

Objectives: To obtain and compare the exact visual status before and afterexcision of sella supra sellar tumors using the computerized perimetry as a standard measuringtools and then compare with the international studies. Background: Sella suprasellar tumorsare though not so common but affect visual acuity of patients and their quality of life drops.These tumors include pituitary adenoma commonest in the adult population, meningioma,Craniopharyngioma, astrocytic glioma, Optic nerve Glioma, Germinoma, Dermoid, Pituitarymetastases. We planned a descriptive case series study to compare the pre and post excisionvisual field defects using computerized perimetry. Study Design: Case series study. Setting:Department of Neurosurgery, Pakistan Institute of Medical Sciences, SZABMU, and Islamabad.Period: 2 years from January 2015 to December 2016. Methods: A total of 73 patients withsella suprasellar tumors were identified and enrolled. Patients between the age of 10 and55 years were selected on the basis of having sella supra sellar tumor on CT/MRI brain withcontrast. Patients whose age was less than 10 years and more than 55 years were excluded.Moreover, patients with post radiation necrosis diagnosed on MRI and MR spectroscopy brain,those operated for other eye pathology and patients with sella supra sellar SOL having comorbiditieslike diabetes mellitus, hypertension etc. were also excluded from the study. Thestudy outcome was measured in terms of comparison of visual field defects after excision ofsella suprasellar tumors using computerized perimetry. Results: The average age of patientswas 42.1 + 6.8 years ranging from 10 to 55 years. Female gender was predominant; therewere 40 (54.8%) female patients. The mean computerized perimetry was 0.65 + 0.34 LogMARbefore surgery which improved to 0.19 + 0.12 LogMAR after surgery. Overall, of the 73 cases,63 (86.4%) had improvement whereas 10 (13.6%) study cases had no improvement in thevisual field on follow-up. Conclusion: It can be concluded that after craniotomy and excisionof sella suprasellar tumors, perimetry showed improvement in the majority of the study cases.


1964 ◽  
Vol 2 (5) ◽  
pp. 18-19

In chronic simple (open-angle) glaucoma loss of visual field may be prevented by improving the outflow of aqueous humour from the eye and thus lowering the raised intra-ocular pressure. This is achieved mainly by miotic drugs which constrict the pupil and make the ciliary muscle contract. These either mimic acetylcholine, acting directly on the ciliary muscle, or inhibit cholinesterase and so allow acetylcholine to accumulate.


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