Acceleration of epithelial keratinization by carcinogens in fetal rat forestomach in organ culture

1984 ◽  
Vol 46 (1) ◽  
pp. 205-213 ◽  
Author(s):  
H. Fukamachi
Keyword(s):  
Organ Culture ◽  
Fetal Rat ◽  
Epithelial Keratinization

Activation of serum complement inhibits collagen synthesis in fetal rat bone in organ culture

1982 ◽  
Vol 34 (1) ◽  
pp. 370-375 ◽  
Author(s):  
Barbara E. Kream ◽  
Lawrence G. Raisz ◽  
Ann L. Sandberg
Keyword(s):  
Organ Culture ◽  
Collagen Synthesis ◽  
Serum Complement ◽  
Fetal Rat ◽  
Rat Bone

Changes in the properties of fetal rat liver during organ culture

In Vitro ◽  
1979 ◽  
Vol 15 (8) ◽  
pp. 579-586
Author(s):  
Carl Monder ◽  
Alena Hatle Coufalik
Keyword(s):  
Organ Culture ◽  
Rat Liver ◽  
Fetal Rat ◽  
Fetal Rat Liver

scholarly journals AMINOPHYLLINE STIMULATES PHOSPHOLIPID SYNTHESIS BY FETAL RAT LUNG IN ORGAN CULTURE

1977 ◽  
Vol 11 (4) ◽  
pp. 571-571 ◽  
Author(s):  
Ian Gross ◽  
Seamus A Rooney ◽  
J B Warshaw
Keyword(s):  
Organ Culture ◽  
Rat Lung ◽  
Phospholipid Synthesis ◽  
Fetal Rat ◽  
Fetal Rat Lung

scholarly journals MORPHOLOGICAL AND BIOCHEMICAL STUDIES OF B CELLS OF FETAL RAT ENDOCRINE PANCREAS IN ORGAN CULTURE

1971 ◽  
Vol 50 (3) ◽  
pp. 565-582 ◽  
Author(s):  
Lelio Orci ◽  
Andre E. Lambert ◽  
Yasunori Kanazawa ◽  
Mylene Amherdt ◽  
Charles Rouiller ◽  
...  
Keyword(s):  
B Cells ◽  
Organ Culture ◽  
Endocrine Pancreas ◽  
De Novo ◽  
Immunoreactive Insulin ◽  
De Novo Synthesis ◽  
Complex Activity ◽  
Golgi Region ◽  
Fetal Rat ◽  
Silver Grains

Fetal rat pancreases explanted on the 18th day of gestation and maintained in organ culture for 1–10 days were utilized for this series of studies. Ultrastructurally, at the time of explantation, the majority of fetal B cells was sparsely granulated and characterized by numerous free ribosomes and undeveloped rough endoplasmic reticulum (RER) and Golgi complexes. During the culture period, extensive development of the RER and Golgi complexes preceded an increasing accumulation of ß-granules. This later increase in the number of ß-granules and in the concentration of immunoreactive insulin was paralleled by a reduction of RER and Golgi complex activity. High resolution radioautographic studies of pulse-chase experiment over a 1 hr period demonstrated the shift of silver grains from the elements of the RER, through the Golgi region, and finally to the ß-granules. Incubation with 14C-labeled leucine demonstrated the incorporation of radioactivity into molecules possessing the immunological and electrophoretic properties of insulin. These studies indicate that de novo synthesis of (pro)insulin occurs also during culture of fetal rat pancreas explanted relatively late in gestation.

Effects of ammonium chloride on resorption of fetal rat bones in organ culture

1984 ◽  
Vol 246 (6) ◽  
pp. E516-E518
Author(s):  
A. J. Johannesson ◽  
L. G. Raisz
Keyword(s):  
Parathyroid Hormone ◽  
Bone Resorption ◽  
Organ Culture ◽  
Ammonium Chloride ◽  
Lysosomal Enzyme ◽  
Potent Inhibitor ◽  
Lysosomal Function ◽  
Fetal Rat ◽  
45Ca Release

Ammonium chloride, a known inhibitor of lysosomal function, was found to be a rapid and potent inhibitor of 45Ca release from fetal rat bones in organ culture. The response to parathyroid hormone and prostaglandin E2 was inhibited in a dose-related, reversible fashion. The activity of the lysosomal enzyme beta-glucuronidase in the medium closely paralleled 45Ca release. Ammonium chloride may now be added to the list of antilysosomal agents that inhibit bone resorption in vitro.

Sensitivity of the Fetal Rat Pituitary-Adrenal System to Corticotropin-Releasing Factor in Organ Culture

1992 ◽  
Vol 145 (1) ◽  
pp. 88-92
Author(s):  
M. Yamamoto ◽  
K. Arishima ◽  
T. Takizawa ◽  
M. Shirai ◽  
Y. Eguchi
Keyword(s):  
Organ Culture ◽  
Corticotropin Releasing Factor ◽  
Adrenal System ◽  
Fetal Rat ◽  
Rat Pituitary
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