Dye- and gamma probe-guided sentinel lymph node biopsy in breast cancer patients: using patent blue dye and technetium-99m-labeled human serum albumin

Breast Cancer ◽  
2000 ◽  
Vol 7 (1) ◽  
pp. 87-94 ◽  
Author(s):  
Koichiro Tsugawa ◽  
Masakuni Noguchi ◽  
Koichi Miwa ◽  
Etsuro Bando ◽  
Kunihiko Yokoyama ◽  
...  
2008 ◽  
Vol 90 (4) ◽  
pp. 338-339 ◽  
Author(s):  
Sophocles Lanitis ◽  
George Filippakis ◽  
Virinder Sidhu ◽  
Ragheed AL Mufti ◽  
Tak H Lee ◽  
...  

INTRODUCTION We present an unusual case of severe anaphylaxis to Patent Blue dye with atypical clinical features during sentinel lymph node biopsy (SLNB). The medical personnel involved with sentinel node biopsies should be alert, and familiar with this unusual entity. We also present current data from the literature. CASE REPORT During a wide local excision for primary breast cancer and SLNB, and early during the operation, the patient became severely tachycardic and hypotensive without any signs of urticaria, rash, oedema, or bronchospasm. Resuscitation required the addition of noradrenaline infusion followed by an overnight admission to the intensive care unit. Raised serum tryptase levels supported the diagnosis of anaphylactic shock while skin tests showed a severe reaction to Patent Blue dye. CONCLUSIONS Severe, life-threatening anaphylaxis to Patent Blue dye may present without obvious previous exposure to the dye and without the cardinal signs of oedema, urticaria and bronchospasm making the diagnosis and management of such cases challenging. Correct diagnosis and identification of the causative factor is important and requires a specific set of laboratory tests that are not commonly requested in every-day medical practice. It is not clear from the literature whether the condition is common enough to justify pre-operative prophylactic or diagnostic measures.


2001 ◽  
Vol 27 (2) ◽  
pp. 218-219 ◽  
Author(s):  
M.H. Mullan ◽  
S.J. Deacock ◽  
N.F. Quiney ◽  
M.W. Kissin

2013 ◽  
Vol 154 (50) ◽  
pp. 1991-1997 ◽  
Author(s):  
Zoltán Mátrai ◽  
Ferenc Bánhidy ◽  
Melinda Téglás ◽  
Eszter Kovács ◽  
Ákos Sávolt ◽  
...  

The incidence of pregnancy-associated breast cancer is rising. Sentinel lymph node biopsy is the method of choice in clinically node negative cases as the indicated minimally invasive regional staging procedure. Some reports have linked radioisotope and blue dye required for lymphatic mapping to teratogenic effects, the idea of which has become a generalized statement and, until recently, contraindication for these agents was considered during pregnancy. Today, there are many published reports of successful interventions with low-dose 99mTc-labeled human albumin nanocolloid, based on dosimetric modeling demonstrating a negligible radiation exposure of the fetus. These results contributed to the seemingly safe and successful use of sentinel lymph node biopsy during pregnancy, though generally it can not replace axillary lymphadenectomy in the absence of high-quality evidence. The possibility of sentinel lymph node biopsy should be offered to pregnancy-associated early breast cancer patients with clinically negative axilla, and patients should be involved in the decision making following extensive counselling. This paper presents the successful use of sentinel lymph node biopsy with low-dose tracer during two pregnancies (in the first and third trimesters) and, for the first time in Hungarian language, it offers a comprehensive literature review on this topic. Orv. Hetil., 154(50), 1991–1997.


2021 ◽  
Vol 36 (6) ◽  
Author(s):  
Heloisa Magda Resende ◽  
Martina Lichtenfels ◽  
Igor Camargo Soares ◽  
Angélica Araújo Cortines Laxe Renó ◽  
Ana Paula Cunha ◽  
...  

2005 ◽  
Vol 12 (9) ◽  
pp. 712-717 ◽  
Author(s):  
Amy C. Degnim ◽  
Kevin Oh ◽  
Vincent M. Cimmino ◽  
Kathleen M. Diehl ◽  
Alfred E. Chang ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document