Positron emission tomography applied in the study of pituitary adenomas

1991 ◽  
Vol 14 (6) ◽  
pp. 509-528 ◽  
Author(s):  
Carin Muhr ◽  
M. Bergström
Keyword(s):  
Positron Emission Tomography ◽  
Pituitary Adenomas ◽  
Emission Tomography ◽  
Positron Emission

Amino Acid Distribution and Metabolism in Pituitary Adenomas Using Positron Emission Tomography with D-[11C]Methionine and L-[11C]Methionine

1987 ◽  
Vol 11 (3) ◽  
pp. 384-389 ◽  
Author(s):  
Mats Bergström ◽  
Carin Muhr ◽  
Per Olov Lundberg ◽  
Kjell Bergström ◽  
Hans Lundqvist ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Amino Acid ◽  
Pituitary Adenomas ◽  
Emission Tomography ◽  
Amino Acid Distribution ◽  
Positron Emission

scholarly journals SUN-458 Use of Positron Emission Tomography in Pituitary Adenomas in Uruguay: a Case Series

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Maria Pineyro ◽  
Mariana Risso ◽  
Paula Montiglia ◽  
Andres Damian ◽  
Ramiro Lima ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Pituitary Adenomas ◽  
Case Series ◽  
Emission Tomography ◽  
Positron Emission

Ectopic Adrenocorticotropic Hormone–Secreting Pituitary Adenomas: An Underestimated Entity

Neurosurgery ◽  
2017 ◽  
Vol 80 (4) ◽  
pp. 525-533 ◽  
Author(s):  
Ulrich J. Knappe ◽  
Christian Jaspers ◽  
Desirée Buschsieweke ◽  
Wolf-Dieter Reinbold ◽  
Ali Alomari ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Pituitary Adenomas ◽  
Adrenocorticotropic Hormone ◽  
Somatostatin Receptor ◽  
Emission Tomography ◽  
Cushing Disease ◽  
Ectopic Acth ◽  
Positron Emission ◽  
Acth Secreting

AbstractBACKGROUND: The diagnosis of Cushing disease is based on endocrinological pa-rameters, with no single test being specific. In some patients, dynamic thin-slice sellar magnetic resonance imaging fails to detect a pituitary tumor.OBJECTIVE: The purpose of this study is to investigate the role of ectopic pituitary adenoma in this situation.METHODS: In a retrospective chart review, 5 patients (6%) with ectopic adenomas were identified in 83 consecutive patients undergoing transsphenoidal surgery for adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas by 1 surgeon.RESULTS: In all 5 patients (all female, 32-41 years of age), an exclusively extrasellar ACTH-secreting adenoma was excised. Three adenomas were located in the cavernous sinus, 1 in the sphenoid sinus, and 1 in the ethmoidal cells. Histologically, none of the tumors showed signs of aggressiveness. Three of the 5 adenomas specifically expressed somatostatin receptor 5. In 4 patients with Cushing disease, postoperative remission was obtained, with 1 recurrence after 14 months. In the patient with Nelson syndrome, ACTH decreased from >800 to <80 pg/mL. Three patients underwent previous surgery elsewhere, including 1 hypophysectomy. In this case, the ectopic adenoma (positive for somatostatin receptor 5) in the ethmoidal cells turned out to be positive on gallium 68 DOTATATE positron emission tomography/computed tomography.CONCLUSION: The incidence of primarily ectopic ACTH-secreting adenomas in this series was 6%. In cases of negative MRI findings, an ectopic ACTH-secreting adenoma should be taken into account. 68Ga DOTATATE positron emission tomography/computed tomography may identify ectopic pituitary adenomas. Hypophysectomy should always be avoided in primary surgery for CD.

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