Impact of Cadmium and Zinc Prior Exposure on 110m Silver, 58+60 Cobalt and 137 Cesium Uptake by Two Freshwater Bivalves During a Brief Field Experiment

C. Adam; B. Fraysse; J. Garnier-Laplace; J. P. Baudin; A. Boudou

doi:10.1007/s001280272

Impact of Cadmium and Zinc Prior Exposure on 110m Silver, 58+60 Cobalt and 137 Cesium Uptake by Two Freshwater Bivalves During a Brief Field Experiment

Bulletin of Environmental Contamination and Toxicology ◽

10.1007/s001280272 ◽

2002 ◽

Vol 68 (3) ◽

pp. 428-435

Author(s):

C. Adam ◽

B. Fraysse ◽

J. Garnier-Laplace ◽

J. P. Baudin ◽

A. Boudou

Keyword(s):

Field Experiment ◽

Prior Exposure ◽

Freshwater Bivalves ◽

Cesium Uptake

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Impact of Cadmium and Zinc Prior Exposure on 110mSilver, 58+60Cobalt and 137Cesium Uptake by Two Freshwater Bivalves During a Brief Field Experiment

Bulletin of Environmental Contamination and Toxicology ◽

10.1007/s00128-001-0272-y ◽

2002 ◽

Vol 68 (3) ◽

pp. 0428-0435

Author(s):

C. Adam ◽

B. Fraysse ◽

J. Garnier-Laplace ◽

J. P. Baudin ◽

A. Boudou

Keyword(s):

Field Experiment ◽

Prior Exposure ◽

Freshwater Bivalves

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Potentiation of bromotrichloromethane hepatotoxicity in male rats exposed to 10 ppm dietary chlordecone: Electron Microscopic and biochemical study

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100158972 ◽

1990 ◽

Vol 48 (3) ◽

pp. 284-285

Author(s):

O. M. Faroon ◽

R. W. Henry ◽

M. G. Soni ◽

H. M. Mehendale

Keyword(s):

Free Radical ◽

Biochemical Study ◽

Prior Exposure ◽

Male Rats ◽

Cellular Injury ◽

Low Doses ◽

Mixed Function Oxidase ◽

Electron Microscopic ◽

Potent Inducer ◽

Cellular Energy

Previous work has shown that mirex undergoes photolytic dechlorination to chlordecone (CD) (KeponeR) in the environment. Much work has shown that prior exposure to nontoxic levels of CD causes potentiation of hepatotoxicity and lethality of CCl4, BrCCl3 and other halomethane compounds. Potentiation of bromotrichloromethane hepatotoxicity has been associated with compounds that stimulate the activity of hepatic mixed-function oxidase (MFO). An increase in the metabolism of halomethane by the MFO to a free radical initiates peroxidative decomposition of membranal lipids ending in massive cellular injury. However, not all MFO inducers potentiate BrCCl3 hepatotoxicity. Potentiation by much larger doses of phenobarbital is minimal and th at by a more potent inducer of MFO, mirex, is negligible at low doses. We suggest that the CD and bromotrichloromethane interaction results in a depletion of cellular energy and thereby reducing the cellular ability to undergo mitosis.

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