Increased lateral femoral condyle ratio is associated with greater risk of ALC injury in non-contact anterior cruciate ligament injury

2020 ◽  
Author(s):  
Ke Li ◽  
Xiaoqing Zheng ◽  
Jia Li ◽  
Rebecca A. Seeley ◽  
Vincent Marot ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Anterior Cruciate Ligament Injury ◽  
Femoral Condyle ◽  
Cruciate Ligament ◽  
Lateral Femoral Condyle ◽  
Ligament Injury ◽  
Anterior Cruciate

An Increased Lateral Femoral Condyle Ratio Is a Risk Factor for Anterior Cruciate Ligament Injury

2018 ◽  
Vol 100 (10) ◽  
pp. 857-864 ◽  
Author(s):  
Thomas R. Pfeiffer ◽  
Jeremy M. Burnham ◽  
Jonathan D. Hughes ◽  
Ajay C. Kanakamedala ◽  
Elmar Herbst ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Risk Factor ◽  
Anterior Cruciate Ligament Injury ◽  
Femoral Condyle ◽  
Cruciate Ligament ◽  
Lateral Femoral Condyle ◽  
Ligament Injury ◽  
Anterior Cruciate

scholarly journals Peripheral shift in the viable chondrocyte population of the medial femoral condyle after anterior cruciate ligament injury in the porcine knee

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256765
Author(s):  
Meggin Q. Costa ◽  
Martha M. Murray ◽  
Jakob T. Sieker ◽  
Naga Padmini Karamchedu ◽  
Benedikt L. Proffen ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Anterior Cruciate Ligament Injury ◽  
Cell Injury ◽  
Femoral Condyle ◽  
Cruciate Ligament ◽  
Medial Femoral Condyle ◽  
Ligament Injury ◽  
Post Injury ◽  
Ki 67 ◽  
Anterior Cruciate

Anterior cruciate ligament injuries result in posttraumatic osteoarthritis in the medial compartment of the knee, even after surgical treatment. How the chondrocyte distribution within the articular cartilage changes early in this process is currently unknown. The study objective was to investigate the chondrocyte distribution within the medial femoral condyle after an anterior cruciate ligament transection in a preclinical model. Forty-two adolescent Yucatan minipigs were allocated to receive unilateral anterior cruciate ligament surgery (n = 36) or no surgery (n = 6). Central coronal sections of the medial femoral condyle were obtained at 1- and 4 weeks after surgery, and the chondrocyte distribution was measured via whole slide imaging and a cell counting batch processing tool utilized in ImageJ. Ki-67 immunohistochemistry was performed to identify proliferating cells. Empty lacunae, karyolysis, karyorrhexis, and pyknosis were used to identify areas of irreversible cell injury. The mean area of irreversible cell injury was 0% in the intact controls, 13.4% (95% confidence interval: 6.4, 20.3) at 1-week post-injury and 19.3% (9.7, 28.9) at 4 weeks post-injury (p < .015). These areas occurred closest to the femoral intra-articular notch. The remaining areas containing viable chondrocytes had Ki-67-positive cells (p < .02) and increased cell density in the middle (p < .03) and deep zones (p = .001). For the entire section, the total chondrocyte number did not change significantly post-operatively; however, the density of cells in the peripheral regions of the medial femoral condyle increased significantly at 1- and 4 weeks post-injury relative to the intact control groups (p = .032 and .004, respectively). These data demonstrate a peripheral shift in the viable chondrocyte population of the medial femoral condyle after anterior cruciate ligament injury and further suggest that chondrocytes with the capacity to proliferate are not confined to one particular cartilage layer.

scholarly journals Anterior Cruciate Ligament Injury and its Rehabilitation in Nepal

2021 ◽  
Vol 59 (239) ◽  
Author(s):  
Suraj Bhusal ◽  
Ujjwal Dotel ◽  
Shamed Kumar Katila ◽  
Saugat Shrestha
Keyword(s):  
Anterior Cruciate Ligament ◽  
Anterior Cruciate Ligament Injury ◽  
Tibial Plateau ◽  
Treatment Approach ◽  
Femoral Condyle ◽  
Cruciate Ligament ◽  
Return To Play ◽  
Ligament Injury ◽  
Medial Aspect ◽  
Anterior Cruciate

Anterior cruciate ligament is one of the most common ligaments to get injured especially in athletic population. It is a band of dense connective tissue which arises from the antero-medial aspect of the inter condylar area on the tibial plateau and passes upwards and backwards to attach to the posteromedial aspect of the lateral femoral condyle. There is increasing rate of its reported injuries among athletes in Nepal and surgeons report increased consultations among athletes regarding adequate intervention strategies. Factors like over use, inadequate recovery time, playing surface, fitness incompatibility are involved in the increase of anterior cruciate ligament injury among athletes in Nepal. Treatment approach for anterior cruciate ligament injury is ever evolving with regular studies and innovation, but constant guidance and rehabilitation in an institution-based setting have shown positive feedback in recovery and return to play.

Anterior cruciate ligament injury risk factors in football

2019 ◽  
Vol 59 (10) ◽  
Author(s):  
Gian Nicola Bisciotti ◽  
Karim Chamari ◽  
Emanuele Cena ◽  
Andrea Bisciotti ◽  
Alessandro Bisciotti ◽  
...  
Keyword(s):  
Risk Factors ◽  
Anterior Cruciate Ligament ◽  
Anterior Cruciate Ligament Injury ◽  
Injury Risk ◽  
Cruciate Ligament ◽  
Ligament Injury ◽  
Injury Risk Factors ◽  
Anterior Cruciate
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