Reducing effect of the novel positive allosteric modulator of the GABAB receptor, COR659, on binge-like alcohol drinking in male mice and rats

2021 ◽  
Author(s):  
Irene Lorrai ◽  
Chase Shankula ◽  
Jorge Marquez Gaytan ◽  
Tomoya Kawamura ◽  
Paola Maccioni ◽  
...  
Keyword(s):  
Alcohol Drinking ◽  
Gabab Receptor ◽  
Allosteric Modulator ◽  
The Novel ◽  
Male Mice ◽  
Positive Allosteric Modulator

Efficacy and side effects of baclofen and the novel GABAB receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction

2018 ◽  
Vol 235 (7) ◽  
pp. 1955-1965 ◽  
Author(s):  
Valentina Vengeliene ◽  
Tatiane T. Takahashi ◽  
Olga A. Dravolina ◽  
Irina Belozertseva ◽  
Edwin Zvartau ◽  
...  
Keyword(s):  
Side Effects ◽  
Animal Models ◽  
Gabab Receptor ◽  
Cocaine Addiction ◽  
Allosteric Modulator ◽  
The Novel ◽  
Positive Allosteric Modulator

scholarly journals Reduction of excessive alcohol drinking by a novel GABAB receptor positive allosteric modulator ADX71441 in mice

2013 ◽  
Vol 231 (2) ◽  
pp. 333-343 ◽  
Author(s):  
Lara S. Hwa ◽  
Mikhail Kalinichev ◽  
Hasnaà Haddouk ◽  
Sonia Poli ◽  
Klaus A. Miczek
Keyword(s):  
Alcohol Drinking ◽  
Gabab Receptor ◽  
Allosteric Modulator ◽  
Positive Allosteric Modulator ◽  
Excessive Alcohol

In vitro and in vivo characterization of the novel GABAB receptor positive allosteric modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE)

2011 ◽  
Vol 61 (5-6) ◽  
pp. 957-966 ◽  
Author(s):  
Elisabetta Perdona’ ◽  
Vivian J.A. Costantini ◽  
Michela Tessari ◽  
Prisca Martinelli ◽  
Corrado Carignani ◽  
...  
Keyword(s):  
Gabab Receptor ◽  
Allosteric Modulator ◽  
The Novel ◽  
Positive Allosteric Modulator ◽  
In Vivo Characterization

Characterization of the Novel Positive Allosteric Modulator, LY2119620, at the Muscarinic M2and M4Receptors

2014 ◽  
Vol 86 (1) ◽  
pp. 106-115 ◽  
Author(s):  
Carrie H. Croy ◽  
Douglas A. Schober ◽  
Hongling Xiao ◽  
Anne Quets ◽  
Arthur Christopoulos ◽  
...  
Keyword(s):  
Allosteric Modulator ◽  
The Novel ◽  
Positive Allosteric Modulator

scholarly journals 0003 Effects Of A Novel GABAB Receptor Positive Allosteric Modulator, ASP8062, On Sleep And Electroencephalogram Activity In Rats

SLEEP ◽  
2018 ◽  
Vol 41 (suppl_1) ◽  
pp. A1-A1
Author(s):  
N Murai ◽  
Y Kondo ◽  
S Akuzawa ◽  
T Mihara ◽  
N Shiraishi ◽  
...  
Keyword(s):  
Gabab Receptor ◽  
Allosteric Modulator ◽  
Positive Allosteric Modulator

[P4-036]: THE NOVEL AMPA RECEPTOR POSITIVE ALLOSTERIC MODULATOR S 47445 RESCUES IN VIVO CA3-CA1 LONG-TERM POTENTIATION AND STRUCTURAL SYNAPTIC CHANGES IN MIDDLE-AGED MICE

2017 ◽  
Vol 13 (7S_Part_26) ◽  
pp. P1270-P1270
Author(s):  
Sylvie Bretin ◽  
Albert Giralt ◽  
María Ángeles Gómez-Climent ◽  
Rafael Alcalá ◽  
Jose Maria Delgado-Garcia ◽  
...  
Keyword(s):  
Ampa Receptor ◽  
Long Term Potentiation ◽  
Allosteric Modulator ◽  
The Novel ◽  
Positive Allosteric Modulator ◽  
Aged Mice ◽  
Term Potentiation ◽  
Synaptic Changes
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