Non-ischemic cerebral enhancing lesions secondary to endovascular aneurysm therapy: nickel allergy or foreign body reaction? Case series and review of the literature

Background: Artificial ligaments have been developed and used in the treatment of ligamentous injuries since the 1970s. The early generation of artificial ligaments showed promising short-term results but resulted in high rates of rupture and inflammatory reaction in the surrounding tissues. Purpose: To determine whether the use of Ligament Augmentation and Reconstruction System (LARS) ligaments is associated with the development of intra-articular foreign body reaction. Study Design: Case series; Level of evidence, 4. Methods: LARS ligaments were explanted from 15 patients under 6 consultant orthopaedic surgeons at 8 surgical centers. Of these, 14 explanted samples were sent for macroscopic and histological analysis, with the 1 remaining sample sent for scanning electron microscopy, to assess for inflammatory change as well as the degree of fibrous tissue ingrowth. Results: We observed a foreign body reaction in 10 of 14 explanted LARS ligaments. Seven samples demonstrated fibrous tissue ingrowth, with 5 producing only focal or incomplete ingrowth. The 2 samples with extensive fibrous coverage were completely free of any foreign body reaction, while all 5 remaining samples with only focal or partial fibrous ingrowth were associated with at least some degree of harmful immune response. Conclusion: The LARS ligament is still associated with a clinically significant degree of foreign body reaction despite the LARS Company’s efforts to reduce complications through improved design. The development and completion of fibrous tissue ingrowth may work to reduce the occurrence of a foreign body reaction.

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Pediatric Recurrent Intentional Foreign Body Ingestion: Case Series and Review of the Literature

Journal of Pediatric Gastroenterology and Nutrition ◽

10.1097/mpg.0000000000002757 ◽

2020 ◽

Vol 71 (2) ◽

pp. 232-236

Author(s):

Christina M. Low Kapalu ◽

Nadia Ibrahimi ◽

Janelle M. Mentrikoski ◽

Thomas Attard

Keyword(s):

Foreign Body ◽

Case Series ◽

Foreign Body Ingestion ◽

Review Of The Literature

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Foreign-body reaction to silastic burr-hole covers with seroma formation: Case report and review of the literature

Pathology - Research and Practice ◽

10.1016/s0344-0338(00)80023-0 ◽

2000 ◽

Vol 196 (1) ◽

pp. 61-66 ◽

Cited By ~ 6

Author(s):

Peter A. Winkler ◽

Christopher Herzog ◽

Christoph Weiler ◽

Kartik G. Krishnan

Keyword(s):

Case Report ◽

Foreign Body ◽

Foreign Body Reaction ◽

Seroma Formation ◽

Burr Hole ◽

Review Of The Literature

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Idiopathic Orofacial Granulomatosis with Varied Clinical Presentation

Case Reports in Dentistry ◽

10.1155/2013/701749 ◽

2013 ◽

Vol 2013 ◽

pp. 1-3

Author(s):

Rathy Ravindran ◽

Anila Karunakaran

Keyword(s):

Foreign Body ◽

Foreign Body Reaction ◽

Clinical Presentation ◽

Signs And Symptoms ◽

Mycobacterial Infection ◽

Granulomatous Disease ◽

Review Of The Literature ◽

Orofacial Granulomatosis ◽

Oral Manifestation ◽

Orofacial Region

Orofacial granulomatosis is a granulomatous disease of orofacial region, which can occur for a variety of reasons. The clinical features are highly variable and sometimes so insidious that signs and symptoms are not frequently severe to cause alarm. The lips are most commonly involved with persistent/recurrent swelling. The medical history is very important as Crohn’s disease and sarcoidosis can present oral manifestation. Other causes like mycobacterial infection, foreign body reaction, fungal infection, and allergy were excluded with further investigation to establish diagnosis. Here and we report a case of orofacial granulomatosis with a review of the literature.

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