scholarly journals Foreign Body Reaction Associated With Artificial LARS Ligaments: A Retrieval Study

2018 ◽  
Vol 6 (12) ◽  
pp. 232596711881160 ◽  
Author(s):  
Zachary Paul Sinagra ◽  
Alan Kop ◽  
Moreica Pabbruwe ◽  
Jeremy Parry ◽  
Gavin Clark
Keyword(s):  
Foreign Body ◽  
Foreign Body Reaction ◽  
Fibrous Tissue ◽  
Case Series ◽  
Significant Degree ◽  
Level Of Evidence ◽  
Tissue Ingrowth ◽  
Artificial Ligaments ◽  
Clinically Significant ◽  
Improved Design

Background: Artificial ligaments have been developed and used in the treatment of ligamentous injuries since the 1970s. The early generation of artificial ligaments showed promising short-term results but resulted in high rates of rupture and inflammatory reaction in the surrounding tissues. Purpose: To determine whether the use of Ligament Augmentation and Reconstruction System (LARS) ligaments is associated with the development of intra-articular foreign body reaction. Study Design: Case series; Level of evidence, 4. Methods: LARS ligaments were explanted from 15 patients under 6 consultant orthopaedic surgeons at 8 surgical centers. Of these, 14 explanted samples were sent for macroscopic and histological analysis, with the 1 remaining sample sent for scanning electron microscopy, to assess for inflammatory change as well as the degree of fibrous tissue ingrowth. Results: We observed a foreign body reaction in 10 of 14 explanted LARS ligaments. Seven samples demonstrated fibrous tissue ingrowth, with 5 producing only focal or incomplete ingrowth. The 2 samples with extensive fibrous coverage were completely free of any foreign body reaction, while all 5 remaining samples with only focal or partial fibrous ingrowth were associated with at least some degree of harmful immune response. Conclusion: The LARS ligament is still associated with a clinically significant degree of foreign body reaction despite the LARS Company’s efforts to reduce complications through improved design. The development and completion of fibrous tissue ingrowth may work to reduce the occurrence of a foreign body reaction.

Posterolateral Elbow Impingement in Professional Boxers

2007 ◽  
Vol 36 (2) ◽  
pp. 328-332 ◽  
Author(s):  
Kars P. Valkering ◽  
Henk van der Hoeven ◽  
Bas C. M. Pijnenburg
Keyword(s):  
Fibrous Tissue ◽  
Case Series ◽  
Normal Function ◽  
Ligament Injury ◽  
Arthroscopic Debridement ◽  
Extension Deficit ◽  
Level Of Evidence ◽  
Elbow Injury ◽  
Special Surgery ◽  
Hospital For Special Surgery

Background Elbow injury is common in boxing, but it has not been reported in the literature. The onset is often a hyperextension trauma caused by a missed hit. Clinically the boxers complain of pain, stiffness, and an extension deficit. Purpose To evaluate the pathogenesis, diagnostic approach, and arthroscopic treatment of elbow injury in boxers, and to compare these with other sports-related elbow injuries. Study Design Case series; Level of evidence, 4. Methods Between 2003 and 2005, a group of 5 professional boxers received a diagnosis of posterior elbow impingement. An arthroscopic debridement was performed. All patients were evaluated preoperatively and 1 year postoperatively with the Hospital for Special Surgery Elbow Assessment Scale. Results An arthroscopic partial resection of the posterior olecranon tip was performed, and osteophytes and fibrous tissue were removed in this area. Loose bodies were removed from the elbow in 3 patients. They were present in the posterior compartment in 2 patients and the anterior compartment in 1. The Hospital for Special Surgery score showed satisfactory to good improvement after 1 year in all 5 cases. They all showed a normal function at follow-up and had a full return to their sports activities. In contrast with the valgus extension overload syndrome, our patients did not show any signs of concomitant ulnar collateral ligament injury. Conclusion Posterolateral elbow impingement in boxers is caused by hyperextension trauma. Concomitant medial elbow instability was not present. Standard arthroscopic debridement showed good results.

Non-ischemic cerebral enhancing lesions secondary to endovascular aneurysm therapy: nickel allergy or foreign body reaction? Case series and review of the literature

2016 ◽  
Vol 58 (9) ◽  
pp. 877-885 ◽  
Author(s):  
Eimad Shotar ◽  
Bruno Law-Ye ◽  
Flore Baronnet-Chauvet ◽  
Sinead Zeidan ◽  
Dimitri Psimaras ◽  
...  
Keyword(s):  
Foreign Body ◽  
Foreign Body Reaction ◽  
Case Series ◽  
Review Of The Literature ◽  
Nickel Allergy

Gastrointestinal hemorrhage consequent to foreign body reaction to silk sutures: case series and review

1998 ◽  
Vol 48 (3) ◽  
pp. 299-301 ◽  
Author(s):  
R.Eric Pecha ◽  
Thomas Prindiville ◽  
Ronald Kotfila ◽  
Boris Ruebner ◽  
Anthony T. Cheung ◽  
...  
Keyword(s):  
Foreign Body ◽  
Gastrointestinal Hemorrhage ◽  
Foreign Body Reaction ◽  
Case Series

scholarly journals Reduction of epidural fibrosis after laminectomy in rabbits by omental free graft

2013 ◽  
Vol 58 (No. 1) ◽  
pp. 25-31 ◽  
Author(s):  
N. Brkljaca Bottegaro ◽  
J. Kos ◽  
B. Pirkic ◽  
O. Smolec ◽  
Z. Grabarevic ◽  
...  
Keyword(s):  
Foreign Body ◽  
Dura Mater ◽  
Foreign Body Reaction ◽  
Fibrous Tissue ◽  
Scar Tissue ◽  
Control Group ◽  
Epidural Fibrosis ◽  
Free Graft ◽  
Increased Risk ◽  
Experimental Group

Epidural fibrosis is an extradural scar tissue formed after a laminectomy procedure. It is associated with persistent pain after spinal surgery and an increased risk of complications during revision surgery. The aim of this study was to determine the preventive effects of local application of an omental free graft in minimising spinal epidural fibrosis in a rabbit laminectomy model. Twenty two rabbits were randomly divided in two groups, a control group of seven and an experimental group of 15 animals. A dorsal laminectomy at levels L<sub>1</sub> to L<sub>3 </sub>was performed on each rabbit of both groups. Prior to the laminectomy procedure, the animals from the experimental group were submitted to a laparotomy in order to obtain the free omental graft. The graft was then applied to the same animal at the dural deffect. All rabbits were euthanised six weeks after surgery and spine segments L<sub>1</sub> to L<sub>3</sub> were removed. Histological sections were evaluated for fibrosis intensity at the laminectomy level, the adhesion degree between dura mater and fibrous tissue and the presence of the foreign body reaction. A statistically significant correlation was established for the foreign body reaction presence and belonging to the group, which can be explained by the omental effects on inflammation reduction and healing promotion. The degree of adhesion between the dura mater and fibrous tissue and the intensity of the fibrous tissue at the laminectomy level were lower in the experimental group although the differences were not statistically significant. The use of free omental grafts is thus a promising technique in epidural fibrosis prevention.

Midterm Outcomes of a Synthetic Cartilage Implant for the First Metatarsophalangeal Joint in Advanced Hallux Rigidus

2018 ◽  
Vol 40 (4) ◽  
pp. 374-383 ◽  
Author(s):  
Mark Glazebrook ◽  
Chris M. Blundell ◽  
Dominic O’Dowd ◽  
Dishan Singh ◽  
Gwyneth de Vries ◽  
...  
Keyword(s):  
Case Series ◽  
Metatarsophalangeal Joint ◽  
Hallux Rigidus ◽  
Implant Removal ◽  
Level Of Evidence ◽  
First Metatarsophalangeal Joint ◽  
Patient Reported ◽  
Pain Visual Analog Scale ◽  
Safety Parameters ◽  
Clinically Significant

Background: A prospective, randomized, noninferiority clinical trial of synthetic cartilage implant hemiarthroplasty for hallux rigidus demonstrated functional outcomes and safety equivalent to first metatarsophalangeal (MTP) joint arthrodesis at 24 months. We prospectively assessed safety and efficacy outcomes for synthetic cartilage implant hemiarthroplasty at a minimum of 5 years. Methods: Of 135 eligible patients from the original trial, 112 (83.0%) were enrolled (mean age, 58.2 ± 8.8 years; 87 females). Pain visual analog scale (VAS), Foot and Ankle Ability Measure (FAAM) Activities of Daily Living (ADL), and FAAM Sports subscales were completed preoperatively and 2 and 5 years postoperatively. Great toe active dorsiflexion, weightbearing radiographs, secondary procedures, and safety parameters were also evaluated. Results: At 24 months, 14/152 (9.2%) patients had undergone implant removal and conversion to arthrodesis. In years 2 to 5, 9/119 (7.6%) patients underwent implant removal and conversion to arthrodesis. At mean 5.8 ± 0.7 (range, 4.4-8.0) years’ follow-up, pain VAS, FAAM ADL, and FAAM Sports scores improved by 57.9 ± 18.6 points, 33.0 ± 17.6 points, and 47.9 ± 27.1 points, respectively, from baseline. Clinically significant changes in VAS pain, FAAM ADL, and FAAM Sports were reported by 103/106 (97.2%), 95/105 (90.5%), and 97/104 (93.3%) patients, respectively. Patient-reported outcomes at 24 months were maintained at 5.8 years in patients who were not revised. Active MTP joint peak dorsiflexion was maintained. Ninety-nine of 106 (93.4%) patients would have the procedure again. Conclusion: Clinical and safety outcomes for synthetic cartilage implant hemiarthroplasty observed at 2 years were maintained at 5.8 years. The implant remains a viable treatment option to decrease pain, improve function, and maintain motion for advanced hallux rigidus. Level of Evidence: Level IV, case series.

scholarly journals DIAGNOSIS AND TREATMENT OF RETAINED WOODEN FOREIGN BODIES IN THE EXTREMITIES USING ULTRASOUND

2018 ◽  
Vol 26 (3) ◽  
pp. 198-200 ◽  
Author(s):  
BARIŞ POLAT ◽  
YUNUS ATICI ◽  
TAHSIN GÜRPINAR ◽  
AYŞE ESIN POLAT ◽  
DOĞAÇ KARAGÜVEN ◽  
...  
Keyword(s):  
Foreign Body ◽  
Foreign Bodies ◽  
Case Series ◽  
Level Of Evidence ◽  
Erythrocyte Sedimentation ◽  
Ultrasound Evaluation ◽  
Delayed Extraction ◽  
The Mean ◽  
Palm Of The Hand ◽  
Time Of Admission

ABSTRACT Objective This study investigates ultrasonography as an effective tool for localizing and measuring the depth and size of wooden foreign bodies to perform less invasive and easier surgery without the need for any additional radiological techniques. Methods Fifteen patients were operated to remove foreign bodies in the extremities in 2016. The side of the affected extremity, the material, size, and location of the foreign body and time of admission after injury were noted, along with CRP, WBC, and erythrocyte sedimentation rate; length of incision, surgery duration, and complications were evaluated. Results The mean patient age was 39.66 (range: 6 to 68). Of the total, 8 of the foreign bodies were in the plantar surfaces of the feet, 3 were in the cruris, 2 were in the palm of the hand, and 2 were in the fingers. All patients underwent ultrasound evaluation before surgery. The surgeries lasted less than 10 min in 13 (87%) of the cases and from 10 to 20 min in 2 cases. No complications were observed in any of the patients. Conclusion Delayed extraction of foreign bodies can lead to local infections. Ultrasonography can be a reliable option for diagnosing and localizing radiolucent foreign bodies such as wooden objects. Level of Evidence IV; Case series.

Unfavourable early outcomes of total trapeziectomy with RegJoint™ interposition: a report of 38 osteoarthritic hands in 34 patients

2019 ◽  
Vol 45 (2) ◽  
pp. 167-172
Author(s):  
Simo Mattila ◽  
Ville Haapamäki ◽  
Eero Waris
Keyword(s):  
Computed Tomography ◽  
Foreign Body ◽  
Foreign Body Reaction ◽  
Clinical Results ◽  
Mri Findings ◽  
Level Of Evidence ◽  
Trapeziometacarpal Osteoarthritis ◽  
And Function ◽  
Subjective Outcomes

This retrospective study analysed the results of total trapeziectomy with RegJoint™ interposition in 38 osteoarthritic hands in 34 patients. Patients were evaluated preoperatively, at follow-up visits, and at a mean final follow-up of 33 months (range 20–53) with plain radiographs, computed tomography, as well as with subjective and objective evaluations. Pain decreased and subjective outcomes and function improved significantly. Computed tomography 18 months after operation showed osteolysis in 24 cases. Three patients developed wrist pain 12–18 months after operation with MRI findings of a foreign-body reaction in each case. One of these patients was scheduled for revision surgery. Although the clinical results were satisfactory, the risk of foreign-body reaction and osteolysis is noteworthy. We conclude that the use of RegJoint™ should be reconsidered since the implant probably offers no benefit in the treatment of trapeziometacarpal osteoarthritis. Level of evidence: IV

Foreign body reaction in vaginally eroded and noneroded polypropylene suburethral slings in the female: a case series

2009 ◽  
Vol 20 (12) ◽  
pp. 1473-1476 ◽  
Author(s):  
Tilemachos Kavvadias ◽  
Daniel Kaemmer ◽  
Uwe Klinge ◽  
Stefanie Kuschel ◽  
Bernhard Schuessler
Keyword(s):  
Foreign Body ◽  
Foreign Body Reaction ◽  
Case Series ◽  
Suburethral Slings

Gambling-like video game practices: A cross-sectional study of links with problem gambling and disordered gaming

2019 ◽  
Author(s):  
David Zendle
Keyword(s):  
Video Games ◽  
Problem Gambling ◽  
Video Game ◽  
Large Scale ◽  
Significant Degree ◽  
Cross Sectional Study ◽  
Video Gaming ◽  
Cross Sectional ◽  
Streaming Services ◽  
Clinically Significant

A variety of practices have recently emerged which are related to both video games and gambling. Most prominent of these are loot boxes. However, a broad range of other activities have recently emerged which are also related to both gambling and video games: esports betting, real-money video gaming, token wagering, social casino play, and watching videos of both loot box opening and gambling on game streaming services like Twitch.Whilst a nascent body of research has established the robust existence of a relationship between loot box spending and both problem gambling and disordered gaming, little research exists which examines whether similar links may exist for the diverse practices outlined above. Furthermore, no research has thus far attempted to estimate the prevalence of these activities.A large-scale survey of a representative sample of UK adults (n=1081) was therefore conducted in order to investigate these issues. Engagement in all measured forms of gambling-like video game practices were significantly associated with both problem gambling and disordered gaming. An aggregate measure of engagement was associated with both these outcomes to a clinically significant degree (r=0.23 and r=0.43). Engagement in gambling-like video game practices appeared widespread, with a 95% confidence interval estimating that 16.3% – 20.9% of the population engaged in these activities at least once in the last year. Engagement in these practices was highly inter-correlated: Individuals who engaged in one practice were likely to engage in several more.Overall, these results suggest that the potential effects of the blurring of lines between video games and gambling should not primarily be understood to be due to the presence of loot boxes in video games. They suggest the existence of a convergent ecosystem of gambling-like video game practices, whose causal relationships with problem gambling and disordered gaming are currently unclear but must urgently be investigated.

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