scholarly journals 13N-ammonia myocardial perfusion imaging with a PET/CT scanner: impact on clinical decision making and cost-effectiveness

2007 ◽  
Vol 35 (5) ◽  
pp. 889-895 ◽  
Author(s):  
Patrick T. Siegrist ◽  
Lars Husmann ◽  
Martina Knabenhans ◽  
Oliver Gaemperli ◽  
Ines Valenta ◽  
...  
Keyword(s):  
Decision Making ◽  
Cost Effectiveness ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Ct Scanner ◽  
Pet Ct

scholarly journals The effect of beta blocker withdrawal on adenosine myocardial perfusion imaging

2014 ◽  
Vol 21 (6) ◽  
pp. 1223-1229 ◽  
Author(s):  
C. Hoffmeister ◽  
R. Preuss ◽  
R. Weise ◽  
W. Burchert ◽  
O. Lindner
Keyword(s):  
Decision Making ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Beta Blocker ◽  
Perfusion Imaging ◽  
Clinical Decision Making ◽  
Beta Blockers ◽  
Clinical Decision ◽  
Pet Myocardial Perfusion Imaging ◽  
Adenosine Stress Testing

Abstract Background The effect of beta blockers on myocardial blood flow (MBF) under vasodilators has been studied in several SPECT and PET myocardial perfusion imaging (MPI) studies with divergent results. The present study evaluated the effect of a beta blocker withdrawal on quantitative adenosine MBF and on MPI results. Methods Twenty patients with beta blockers and CAD history were studied with quantitative adenosine N-13 ammonia PET. The first study was performed under complete medication and the second after beta blocker withdrawal. The PET studies were independently read with respect to MPI result and clinical decision making. Results Global MBF showed an increase from 180.2 ± 59.9 to 193.6 ± 60.8 mL·minute−1/100 g (P = .02) after beta blocker withdrawal. The segmental perfusion values were closely correlated (R 2 = 0.82) over the entire range of perfusion values. An essentially different interpretation after beta blocker discontinuation was found in two cases (10%). Conclusion A beta blocker withdrawal induces an increase in adenosine MBF. In the majority of cases, MPI interpretation and decision making are independent of beta blocker intake. If a temporary beta blocker withdrawal before MPI is not possible or was not realized by the patient, it is appropriate to perform adenosine stress testing without loss of the essential MPI result.

Goals of palliative cancer therapy.

1993 ◽  
Vol 11 (2) ◽  
pp. 378-381 ◽  
Author(s):  
F Porzsolt ◽  
I Tannock
Keyword(s):  
Quality Of Life ◽  
Decision Making ◽  
Cost Effectiveness ◽  
Cancer Therapy ◽  
Health Professionals ◽  
Palliative Treatment ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Oncology Practice

The major conclusions of the Workshop on Goals of Palliative Cancer Therapy are as follows: 1. The goals of any cancer therapy should be stated explicitly. 2. If the goal of treatment is palliation, this should be documented according to one of the established and validated methods for assessment of quality of life. Several validated methods are available, and although imperfect, have been shown to give reliable information. 3. The use of simple measures of quality of life (eg, symptom checklists, pain assessment cards) should become routine in oncology practice. The act of introducing such measures improves palliation. 4. Measures of cost-effectiveness should be used more widely in clinical decision making to ensure the appropriate deployment of resources. 5. There must be improved education of all health professionals with regard to the multiple methods for provision of palliative treatment to cancer patients and the assessment of palliation.

Cost-effectiveness of myocardial perfusion imaging: A summary of the currently available literature

2005 ◽  
Vol 12 (6) ◽  
pp. 750-759 ◽  
Author(s):  
R DESPREZ ◽  
L SHAW ◽  
R GILLESPIE ◽  
W JABER ◽  
G NOBLE ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging
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