Embryonic stem cells in ophthalmology: the next step to a potential therapy has been taken. “In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells,” by Haruta M, Sasai Y, Kawasaki H, Amemiya K, Ooto S, Kitada M, Suemori H, Nakatsuji N, Ide C, Honda Y, Takahashi M. (2004) Invest Ophthalmol Vis Sci 45(3):1020–1025

2004 ◽  
Vol 242 (7) ◽  
pp. 533-534
Author(s):  
Norbert Kociok
2004 ◽  
Vol 45 (3) ◽  
pp. 1020 ◽  
Author(s):  
Masatoshi Haruta ◽  
Yoshiki Sasai ◽  
Hiroshi Kawasaki ◽  
Kaori Amemiya ◽  
Sotaro Ooto ◽  
...  

2010 ◽  
Vol 12 (2) ◽  
pp. 223-230 ◽  
Author(s):  
Ivan Vassiliev ◽  
Svetlana Vassilieva ◽  
Luke F.S. Beebe ◽  
Sharon J. Harrison ◽  
Stephen M. McIlfatrick ◽  
...  

2015 ◽  
Vol 6 (1) ◽  
pp. 244-251
Author(s):  
Hongwei Chen ◽  
Yu Mao ◽  
Shufen Wang ◽  
Bin Li ◽  
Jinhuan Wang ◽  
...  

AbstractGlial-restricted precursor (GRP) cells, the earliest glial progenitors for both astrocytes and oligodendrocytes, have been derived from embryos and embryonic stem cells (ESC) in rodents. However, knowledge regarding the equivalent cell type in primates is limited due to restrictions imposed by ethics and resources. Here we report successful derivation and characterization of primate GRP cells from rhesus monkey ESC. The purified monkey GRP cells were A2B5-positive and FGF2-dependent for survival and proliferation. The differentiation assays indicated that they were tri-potential in vitro and bi-potential in vivo. These newly purified GRP cells will help to facilitate understanding of the molecular mechanism of glial development in primates as well as provide a source of therapeutic donor cells for use in neuroregenerative medicine.


2011 ◽  
Vol 20 (11) ◽  
pp. 1829-1845 ◽  
Author(s):  
James W. Rowland ◽  
Jason J. Lee ◽  
Ryan P. Salewski ◽  
Eftekhar Eftekharpour ◽  
Derek van der Kooy ◽  
...  

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