Central visual field change after fornix-based trabeculectomy in Japanese normal-tension glaucoma patients managed under 15 mmHg

2021 ◽  
Author(s):  
Kosuke Nakajima ◽  
Rei Sakata ◽  
Koji Ueda ◽  
Asahi Fujita ◽  
Takashi Fujishiro ◽  
...  
Keyword(s):  
Visual Field ◽  
Normal Tension Glaucoma ◽  
Field Change ◽  
Central Visual Field

scholarly journals Diurnal variation in microcirculation of ocular fundus and visual field change in normal-tension glaucoma

Eye ◽  
2004 ◽  
Vol 18 (7) ◽  
pp. 697-702 ◽  
Author(s):  
T Okuno ◽  
T Sugiyama ◽  
S Kojima ◽  
M Nakajima ◽  
T Ikeda
Keyword(s):  
Visual Field ◽  
Diurnal Variation ◽  
Normal Tension Glaucoma ◽  
Field Change ◽  
Ocular Fundus

scholarly journals Systemic and Ocular Hemodynamic Risk Factors in Glaucoma

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Jaewan Choi ◽  
Michael S. Kook
Keyword(s):  
Risk Factors ◽  
Visual Field ◽  
Open Angle Glaucoma ◽  
Ischemia Reperfusion ◽  
Visual Field Loss ◽  
Normal Tension Glaucoma ◽  
Ocular Blood Flow ◽  
Systemic Hypertension ◽  
Central Visual Field ◽  
Tissue Ischemia

Primary open angle glaucoma (POAG) is a multifactorial disease characterized by progressive retinal ganglion cell death and visual field loss. It is known that alterations in intraocular pressure (IOP), blood pressure (BP), and ocular perfusion pressure (OPP) can play a significant role in the pathogenesis of the disease. Impaired autoregulatory capacity of ocular blood vessels may render tissues vulnerable to OPP changes and potentially harmful tissue ischemia-reperfusion damage. Vascular risk factors should be considered more important in a subgroup of patients with POAG, and especially in patients with normal tension glaucoma (NTG) with evidence of unphysiological BP response. For example, reduction of BP during the nighttime has an influence on OPP, and increased circadian OPP fluctuation, which might stand for unstable ocular blood flow, has been found to be the consistent risk factor for NTG development and progression. Central visual field may be affected more severely than peripheral visual field in NTG patients with higher 24-hour fluctuation of OPP. This review will discuss the current understanding of allegedly major systemic and ocular hemodynamic risk factors for glaucoma including systemic hypertension, arterial stiffness, antihypertensive medication, exaggerated nocturnal hypotension, OPP, and autonomic dysregulation.

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