Does laparoscopic antireflux surgery prevent the occurrence of transient lower esophageal sphincter relaxation?

2003 ◽  
Vol 17 (7) ◽  
pp. 1050-1054 ◽  
Author(s):  
C. Gill Pottruff ◽  
M. Anvari ◽  
F. Bahmeriz ◽  
S. Dutta ◽  
C. J. Allen
Keyword(s):  
Lower Esophageal Sphincter ◽  
Antireflux Surgery ◽  
Laparoscopic Antireflux Surgery ◽  
Lower Esophageal Sphincter Relaxation ◽  
Esophageal Sphincter

Transient Lower Esophageal Sphincter Relaxation in Morbid Obesity

2009 ◽  
Vol 19 (5) ◽  
pp. 595-600 ◽  
Author(s):  
J. H. Schneider ◽  
M. Küper ◽  
A. Königsrainer ◽  
B. Brücher
Keyword(s):  
Morbid Obesity ◽  
Lower Esophageal Sphincter ◽  
Lower Esophageal Sphincter Relaxation ◽  
Esophageal Sphincter

scholarly journals THE PARTICIPATION OF THE NITRERGIC PATHWAY IN INCREASED RATE OF TRANSITORY RELAXATION OF LOWER ESOPHAGEAL SPHINCTER INDUCED BY RECTAL DISTENSION IN DOGS

2014 ◽  
Vol 51 (2) ◽  
pp. 102-106 ◽  
Author(s):  
Michel Santos PALHETA ◽  
José Ronaldo Vasconcelos da GRAÇA ◽  
Armênio Aguiar dos SANTOS ◽  
Liziane Hermógenes LOPES ◽  
Raimundo Campos PALHETA JÚNIOR ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Lower Esophageal Sphincter ◽  
Esophageal Motility ◽  
Control Group ◽  
Rectal Distension ◽  
Evaluation Protocol ◽  
Lower Esophageal Sphincter Relaxation ◽  
Respective Control Group ◽  
Esophageal Sphincter ◽  
Pre Treatment

ContextThe rectal distension in dogs increases the rate of transitory lower esophageal sphincter relaxation considered the main factor causing gastroesophageal reflux.ObjectivesThe aim of this study was evaluate the participation of the nitrergic pathway in the increased transitory lower esophageal sphincter relaxation rate induced by rectal distension in anesthetized dogs.MethodsMale mongrel dogs (n = 21), weighing 10-15 kg, were fasted for 12 hours, with water ad libitum. Thereafter, they were anesthetized (ketamine 10 mg.Kg-1+ xylazine 20 mg.Kg-1), so as to carry out the esophageal motility evaluation protocol during 120 min. After a 30-minute basal period, the animals were randomly intravenous treated whith: saline solution 0.15M (1ml.Kg-1), L-NAME (3 mg.Kg-1), L-NAME (3 mg.Kg-1) + L-Arginine (200 mg.Kg-1), glibenclamide (1 mg.Kg-1) or methylene blue (3 mg.Kg-1). Forty-five min after these pre-treatments, the rectum was distended (rectal distension, 5 mL.Kg-1) or not (control) with a latex balloon, with changes in the esophageal motility recorded over 45 min. Data were analyzed using ANOVA followed by Student Newman-Keuls test.ResultsIn comparison to the respective control group, rectal distension induces an increase in transitory lower esophageal sphincter relaxation. Pre-treatment with L-NAME or methylene blue prevents (P<0.05) this phenomenon, which is reversible by L-Arginine plus L-NAME. However, pretreating with glibenclamide failed to abolish this process.ConclusionsTherefore, these experiments suggested, that rectal distension increases transitory lower esophageal sphincter relaxation in dogs via through nitrergic pathways.

T1883 Upper Esophageal Sphincter Relaxation as a Determinant of Reflux and Symptoms During Transient Lower Esophageal Sphincter Relaxation (TLESR)?

2010 ◽  
Vol 138 (5) ◽  
pp. S-598
Author(s):  
Sabine Roman ◽  
Anita Fareeduddin ◽  
John E. Pandolfino ◽  
Monika A. Kwiatek ◽  
Peter J. Kahrilas
Keyword(s):  
Lower Esophageal Sphincter ◽  
Upper Esophageal Sphincter ◽  
Lower Esophageal Sphincter Relaxation ◽  
Esophageal Sphincter

Esophageal longitudinal muscle contraction: Another component of transient lower esophageal sphincter relaxation (tLESR)?

2001 ◽  
Vol 120 (5) ◽  
pp. A632
Author(s):  
Guoxiang Shi ◽  
John E. Pandolfino ◽  
Raymond J. Joehl ◽  
James G. Brassuer ◽  
Peter J. Kahrilas
Keyword(s):  
Muscle Contraction ◽  
Lower Esophageal Sphincter ◽  
Longitudinal Muscle ◽  
Lower Esophageal Sphincter Relaxation ◽  
Esophageal Sphincter
Sign in / Sign up

Export Citation Format

Share Document