scholarly journals Optical coherence tomography-based patient-specific coronary artery reconstruction and fluid–structure interaction simulation

2019 ◽  
Vol 19 (1) ◽  
pp. 7-20 ◽  
Author(s):  
Jiaqiu Wang ◽  
Phani Kumari Paritala ◽  
Jessica Benitez Mendieta ◽  
Yo Komori ◽  
Owen Christopher Raffel ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Coronary Artery ◽  
Fluid Structure Interaction ◽  
Patient Specific ◽  
Optical Coherence ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Interaction Simulation ◽  
Artery Reconstruction

scholarly journals Combining IVUS and Optical Coherence Tomography for More Accurate Coronary Cap Thickness Quantification and Stress/Strain Calculations: A Patient-Specific Three-Dimensional Fluid-Structure Interaction Modeling Approach

2018 ◽  
Vol 140 (4) ◽  
Author(s):  
Xiaoya Guo ◽  
Don P. Giddens ◽  
David Molony ◽  
Chun Yang ◽  
Habib Samady ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Fluid Structure Interaction ◽  
Three Dimensional ◽  
Patient Specific ◽  
Data Sets ◽  
Optical Coherence ◽  
Stress Strain ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Modeling Approach

Accurate cap thickness and stress/strain quantifications are of fundamental importance for vulnerable plaque research. Virtual histology intravascular ultrasound (VH-IVUS) sets cap thickness to zero when cap is under resolution limit and IVUS does not see it. An innovative modeling approach combining IVUS and optical coherence tomography (OCT) is introduced for cap thickness quantification and more accurate cap stress/strain calculations. In vivo IVUS and OCT coronary plaque data were acquired with informed consent obtained. IVUS and OCT images were merged to form the IVUS + OCT data set, with biplane angiography providing three-dimensional (3D) vessel curvature. For components where VH-IVUS set zero cap thickness (i.e., no cap), a cap was added with minimum cap thickness set as 50 and 180 μm to generate IVUS50 and IVUS180 data sets for model construction, respectively. 3D fluid–structure interaction (FSI) models based on IVUS + OCT, IVUS50, and IVUS180 data sets were constructed to investigate cap thickness impact on stress/strain calculations. Compared to IVUS + OCT, IVUS50 underestimated mean cap thickness (27 slices) by 34.5%, overestimated mean cap stress by 45.8%, (96.4 versus 66.1 kPa). IVUS50 maximum cap stress was 59.2% higher than that from IVUS + OCT model (564.2 versus 354.5 kPa). Differences between IVUS and IVUS + OCT models for cap strain and flow shear stress (FSS) were modest (cap strain <12%; FSS <6%). IVUS + OCT data and models could provide more accurate cap thickness and stress/strain calculations which will serve as basis for further plaque investigations.

Investigation of two-way fluid-structure interaction of blood flow in a patient-specific left coronary artery

2021 ◽  
pp. 1-18
Author(s):  
Abdulgaphur Athani ◽  
N.N.N. Ghazali ◽  
Irfan Anjum Badruddin ◽  
Sarfaraz Kamangar ◽  
Ali E. Anqi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Coronary Artery ◽  
Wall Shear Stress ◽  
Left Coronary Artery ◽  
Fluid Structure Interaction ◽  
Patient Specific ◽  
Hemodynamic Parameters ◽  
Fluid Structure ◽  
Structure Interaction

BACKGROUND: The blood flow in the human artery has been a subject of sincere interest due to its prime importance linked with human health. The hemodynamic study has revealed an essential aspect of blood flow that eventually proved to be paramount to make a correct decision to treat patients suffering from cardiac disease. OBJECTIVE: The current study aims to elucidate the two-way fluid-structure interaction (FSI) analysis of the blood flow and the effect of stenosis on hemodynamic parameters. METHODS: A patient-specific 3D model of the left coronary artery was constructed based on computed tomography (CT) images. The blood is assumed to be incompressible, homogenous, and behaves as Non-Newtonian, while the artery is considered as a nonlinear elastic, anisotropic, and incompressible material. Pulsatile flow conditions were applied at the boundary. Two-way coupled FSI modeling approach was used between fluid and solid domain. The hemodynamic parameters such as the pressure, velocity streamline, and wall shear stress were analyzed in the fluid domain and the solid domain deformation. RESULTS: The simulated results reveal that pressure drop exists in the vicinity of stenosis and a recirculation region after the stenosis. It was noted that stenosis leads to high wall stress. The results also demonstrate an overestimation of wall shear stress and velocity in the rigid wall CFD model compared to the FSI model.

Fluid-structure interaction analysis of a patient-specific right coronary artery with physiological velocity and pressure waveforms

2009 ◽  
Vol 25 (5) ◽  
pp. 565-580 ◽  
Author(s):  
Ryo Torii ◽  
Nigel B. Wood ◽  
Nearchos Hadjiloizou ◽  
Andrew W. Dowsey ◽  
Andrew R. Wright ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Interaction Analysis ◽  
Fluid Structure Interaction ◽  
Patient Specific ◽  
Fluid Structure ◽  
Structure Interaction
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