Respiratory Response to Microinjections of GABA and Penicillin into Various Parts of the Ventral Respiratory Group

2012 ◽  
Vol 153 (2) ◽  
pp. 173-176
Author(s):  
O. A. Vedyasova ◽  
A. M. Kovalyov
2021 ◽  
pp. 1869415
Author(s):  
Andrey Khlopkov ◽  
Oksana Sherstneva ◽  
Maria Ladeynova ◽  
Marina Grinberg ◽  
Lyubov Yudina ◽  
...  

2001 ◽  
Vol 91 (4) ◽  
pp. 1713-1722 ◽  
Author(s):  
Fadi Xu ◽  
Tongrong Zhou ◽  
Tonya Gibson ◽  
Donald T. Frazier

Electrical stimulation of the rostral fastigial nucleus (FNr) alters respiration via activation of local neurons. We hypothesized that this FNr-mediated respiratory response was dependent on the integrity of the nucleus gigantocellularis of the medulla (NGC). Electrical stimulation of the FNr in 15 anesthetized and tracheotomized spontaneously breathing rats significantly altered ventilation by 35.2 ± 11.0% ( P < 0.01) with the major effect being excitatory (78%). This respiratory response did not significantly differ from control after lesions of the NGC via bilateral microinjection of kainic or ibotenic acid (4.5 ± 1.9%; P > 0.05) but persisted in sham controls. Eight other rats, in which horseradish peroxidase (HRP) solution was previously microinjected into the left NGC, served as nonstimulation controls or were exposed to either 15-min repeated electrical stimulation of the right FNr or hypercapnia for 90 min. Histochemical and immunocytochemical data showed that the right FNr contained clustered HRP-labeled neurons, most of which were double labeled with c-Fos immunoreactivity in both electrically and CO2-stimulated rats. We conclude that the NGC receives monosynaptic FNr inputs and is required for fully expressing FNr-mediated respiratory responses.


1957 ◽  
Vol 11 (1) ◽  
pp. 65-71 ◽  
Author(s):  
Ralph H. Kellogg ◽  
Nello Pace ◽  
E. R. Archibald ◽  
Burton E. Vaughan
Keyword(s):  

1997 ◽  
Vol 156 (1) ◽  
pp. 146-154 ◽  
Author(s):  
DIMITRIS GEORGOPOULOS ◽  
IOANNA MITROUSKA ◽  
ZOHEIR BSHOUTY ◽  
KIMBERLY WEBSTER ◽  
DIMITRIS PATAKAS ◽  
...  

2010 ◽  
Vol 9 (10) ◽  
pp. 1448-1454 ◽  
Author(s):  
Yue TAN ◽  
Dong-sheng GAO ◽  
Ling LI ◽  
Xiu-de CHEN ◽  
Ai-hong XU

1973 ◽  
Vol 305 (1) ◽  
pp. 41-51 ◽  
Author(s):  
W.X. Balcavage ◽  
J.L. Lloyd ◽  
J.R. Mattoon ◽  
Tomoko Ohnishi ◽  
Antonio Scarpa

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