A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors

2020 ◽  
Vol 38 (6) ◽  
pp. 1815-1825 ◽  
Author(s):  
Charlotte Lemech ◽  
Natasha Woodward ◽  
Nancy Chan ◽  
Joanne Mortimer ◽  
Louie Naumovski ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Dose Escalation ◽  
Phase 1 ◽  
Prolactin Receptor ◽  
Advanced Solid Tumors ◽  
Antibody Drug Conjugate ◽  
Dose Escalation Study ◽  
Drug Conjugate ◽  
Antibody Drug

scholarly journals Phase 1 dose-escalation study of mirvetuximab soravtansine (IMGN853), a folate receptor α-targeting antibody-drug conjugate, in patients with solid tumors

Cancer ◽  
2017 ◽  
Vol 123 (16) ◽  
pp. 3080-3087 ◽  
Author(s):  
Kathleen N. Moore ◽  
Hossein Borghaei ◽  
David M. O'Malley ◽  
Woondong Jeong ◽  
Shelly M. Seward ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Dose Escalation ◽  
Folate Receptor ◽  
Phase 1 ◽  
Antibody Drug Conjugate ◽  
Dose Escalation Study ◽  
Drug Conjugate ◽  
Antibody Drug

scholarly journals A phase 1, dose-escalation study of PF-06664178, an anti-Trop-2/Aur0101 antibody-drug conjugate in patients with advanced or metastatic solid tumors

2018 ◽  
Vol 36 (5) ◽  
pp. 836-847 ◽  
Author(s):  
Gentry T. King ◽  
Keith D. Eaton ◽  
Brandon R. Beagle ◽  
Christopher J. Zopf ◽  
Gilbert Y. Wong ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Dose Escalation ◽  
Phase 1 ◽  
Antibody Drug Conjugate ◽  
Dose Escalation Study ◽  
Drug Conjugate ◽  
Antibody Drug

Phase 1, open-label, dose-escalation and expansion study of ABBV-399, an antibody drug conjugate (ADC) targeting c-Met, in patients (pts) with advanced solid tumors.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. 2510-2510 ◽  
Author(s):  
John H. Strickler ◽  
John J. Nemunaitis ◽  
Colin D. Weekes ◽  
Ramesh K. Ramanathan ◽  
Eric Angevin ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Dose Escalation ◽  
Phase 1 ◽  
Advanced Solid Tumors ◽  
Antibody Drug Conjugate ◽  
Open Label ◽  
Drug Conjugate ◽  
Label Dose ◽  
Antibody Drug
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