scholarly journals Optical coherence tomography angiography of the macular microcirculation in acute primary angle closure treated with phacoemulsification

2022 ◽  
Author(s):  
Lin Fu ◽  
Yau Kei Chan ◽  
Jia Fang ◽  
Junbo Liu ◽  
Shu Mei Wen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Angle Closure ◽  
Optical Coherence ◽  
Acute Primary Angle Closure ◽  
Primary Angle Closure

scholarly journals Optical Coherence Tomography Angiography of The Macular Microcirculation in Acute Primary Angle Closure Treated With Phacoemulsification

2021 ◽  
Author(s):  
Lin Fu ◽  
Yau Kei Chan ◽  
Jia Fang ◽  
Junbo Liu ◽  
Shumei Wen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Vessel Density ◽  
Angle Closure ◽  
Field Pattern ◽  
Control Group ◽  
Optical Coherence ◽  
Acute Primary Angle Closure ◽  
Primary Angle Closure ◽  
Normal Individuals

Abstract Purpose To measure the changes of macular microcirculation in cases with unilateral acute primary angle closure (APAC) who were managed by phacoemulsification. Methods Patients with unilateral APAC and managed by phacoemulsification were enrolled. The contralateral unaffected eyes were served as fellow group, and normal individuals were recruited as control group. Optical coherence tomography angiography (OCT-A) was performed to analyse the macular whole image vessel density (wiVD) and parafoveal vessel density (pfVD). The retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses were assessed using spectral-domain optical coherence tomography. Results A total of 36 APAC patients and 35 eyes from 35 normal individuals were recruited. In the APAC eyes, the mean wiVD (42.1% ± 3.7%) and pfVD (45.2% ± 3.8%) in the superficial layers (wiVD-SL and pfVD-SL) were both significantly reduced, compared to fellow eyes (45.7% ± 3.1%, 48.7% ±3.1%) and control eyes (44.4% ± 4.7%, 47.4% ± 5.1%) (P < 0.05). They were all statistically correlated with RNFL, GCC, visual field pattern standard deviation (PSD), and mean deviation (MD). Conclusion The macular OCT-A parameters including wiVD-SL and pfVD-SL were significantly reduced in the eyes with APAC compared the fellow unaffected eyes and normal control eyes. They were correlated well with RNFL, GCC, PSD and MD. The macular vessel density parameters may help monitor the progression of APAC.

scholarly journals Peripapillary vessel density measurement of quadrant and clock-hour sectors in primary angle closure glaucoma using optical coherence tomography angiography

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yongdong Lin ◽  
Shirong Chen ◽  
Mingzhi Zhang
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Vessel Density ◽  
Angle Closure ◽  
Optical Coherence ◽  
Diagnostic Ability ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma ◽  
Rnfl Thickness ◽  
Inferior Quadrant

Abstract Background The purpose of this study was to investigate diagnostic ability of peripapillary vessel density of primary angle closure glaucoma (PACG) eyes in quadrant and clock-hour sectors by optical coherence tomography angiography (OCTA). Methods This was a cross-sectional study on forty-one PACG patients (41eyes) and twenty-seven healthy subjects (27 eyes). All subjects underwent OCTA (DRI OCT Triton; Topcon Corporation, Tokyo, Japan) and peripapillary retinal nerve fiber layer (RNFL) thickness imaging with swept-source optical coherence tomography (OCT). The peripapillary vessel density of quadrant and clock-hour sectors was quantified by imageJ software. The diagnostic capability of OCTA and OCT parameters was evaluated by the areas under the receiver operating characteristics curves (AUCs). Pearson correlation analysis or Spearman correlation test was used to evaluate the correlation between vessel density parameters and related factors. Results Compared with the control group, the peripapillary vessel density of glaucomatous group was lower to different degrees in the four quadrants and each clock-hour sectors, and vessel density reduced most at 7 o’clock. The difference between the diagnostic ability of peripapillary vessel density and peripapillary RNFL thickness was not statistically significant, except 4 o’clock and inferior quadrant. The inferior quadrant peripapillary vessel density had the best diagnostic value (AUC0.969), followed by the 7 o’clock vessel density (AUC0.964), average vessel density (AUC0.939) and the 7 o’clock RNFL thickness (AUC0.919). The average peripapillary vessel density was correlated with average RNFL and visual field (VF) mean deviation (P < 0.001). Conclusions In PACG, the diagnostic ability of the peripapillary vessel density is equivalent to the peripapillary RNFL thickness. Understanding spatial characteristics of the peripapillary vessel density in PACG may be helpful for clinical diagnosis and monitoring the progress of diseases.

scholarly journals Optical Coherence Tomography Angiography and Visual Field Progression in Primary Angle Closure Glaucoma

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Harsha L. Rao ◽  
Thanemozhi Srinivasan ◽  
Zia S. Pradhan ◽  
Shruthi Sreenivasaiah ◽  
Dhanaraj A.S. Rao ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Field ◽  
Optical Coherence Tomography Angiography ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Optical Coherence ◽  
Visual Field Progression ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma

Anterior segment optical coherence tomography of acute primary angle closure

2010 ◽  
Vol 248 (6) ◽  
pp. 825-831 ◽  
Author(s):  
Hai Tao Zhang ◽  
Liang Xu ◽  
Wei Fang Cao ◽  
Ya Xing Wang ◽  
Jost B. Jonas
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Angle Closure ◽  
Optical Coherence ◽  
Acute Primary Angle Closure ◽  
Primary Angle Closure

Assessment of Schlemm’s canal in acute primary angle closure: an anterior segment optical coherence tomography study

2018 ◽  
Vol 39 (10) ◽  
pp. 2171-2177
Author(s):  
Tarannum Mansoori ◽  
Appidi Abhinav Reddy ◽  
Naga Chandrika Tumati ◽  
Nagalla Balakrishna
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Angle Closure ◽  
Optical Coherence ◽  
Schlemm’S Canal ◽  
Acute Primary Angle Closure ◽  
Schlemm's Canal ◽  
Primary Angle Closure
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