The importance of prediction for genetic regulatory network (GRNs) makes mathematical modeling a prominent tool. In this paper, we consider weighted pseudo-almost periodic solutions for a class of GRNs with time-varying delays. We establish the existence, uniqueness, and global exponential stability by employing the theory of dichotomy, the fixed point theorem, and differential inequality. A numerical example along with a graphical illustration are presented to support our main results. Our results extend existing GRNs models using almost periodic functions to support a wider range of regulatory processes.