Factors affecting blood pressure profile in pre and postmenopausal women with obstructive sleep apnea hypopnea syndrome

2014 ◽  
Vol 19 (1) ◽  
pp. 169-174 ◽  
Author(s):  
Hua Jun Xu ◽  
Xiao Fei Lan ◽  
Qing Yun Li ◽  
Li Na Zhou ◽  
Xiu Juan Zhang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Postmenopausal Women ◽  
Pressure Profile ◽  
Factors Affecting ◽  
Blood Pressure Profile ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

scholarly journals Blood pressure profiles in patients with arterial hypertension and obstructive sleep apnea in different age groups

2021 ◽  
Vol 27 (5) ◽  
pp. 530-535
Author(s):  
A. N. Kuchmin ◽  
V. V. Ekimov ◽  
D. A. Galaktionov ◽  
I. M. Borisov ◽  
A. A. Sheveliov ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Age Groups ◽  
Pressure Profile ◽  
Control Group ◽  
Apnea Hypopnea Index ◽  
Blood Pressure Profile ◽  
Pressure Profiles ◽  
Obstructive Sleep

Background. Obstructive sleep apnea (OSA) is frequently associated with hypertension (HTN), and about 50 % hypertensive patients have concomitant OSA. Episodes of transient upper airway obstruction affect the daily blood pressure profile, leading to nocturnal HTN. Although the general relationship between OSA and the daily blood pressure profile is known, the association between the frequency of various daily blood pressure profiles and OSA severity as well as the age-specific differences remain unknown. The aim of the study was to determine the daily blood pressure profiles in patients with HTN and OSA, depending on the OSA severity and age. Design and methods. The study included 236 HTN patients underwent treatment in the period from 2008 to 2021 years and were diagnosed with OSA by cardiorespiratory monitoring: 84 patients had mild OSA (apnea/hypopnea index (AHI) < 15 episodes/h), 46 patients — moderate OSA (15 ≤ AHI < 30 episodes/h), and 106 patients — severe OSA (AHI ≥ 30 episodes/h). The control group included 140 HTN patients without OSA. Both groups were divided into 3 age subgroups: younger than 45 years, 45–59 years and ≥ 60 years. At baseline, all patients underwent cardiorespiratory monitoring (“Kardiotekhnika‑07–3/12P”, Inkart, St Petersburg, Russia) and 24-hour blood pressure (BP) monitoring (BPLab, Nizhny Novgorod, Russia). Results. We found an association between the distribution of daily BP profiles and age, which differs from that in HTN patients without OSA. Non-dipper and night-peaker BP profiles are predominant in young and middle age. Among OSA patients, the severity of OSA was associated with the BP profiles only in the young and middleage groups. Unfavorable BP profiles (non-dipper and night-peaker) were more common in patients with severe OSA, which was not observed in elderly subgroup. In the elderly, compared to younger patients, the overdipper profile was the most common and its frequency was not associated with OSA severity. Conclusions. The study shows the relationship between the age of patients with HTN and OSA, the OSA severity and the distribution of daily BP profiles.

Z-palatopharyngoplasty for obstructive sleep apnea/hypopnea syndrome

2009 ◽  
Vol 140 (5) ◽  
pp. 640-645 ◽  
Author(s):  
Hong L. Yi ◽  
Shan K. Yin ◽  
Yu J. Zhang ◽  
Bin Chen ◽  
Wen Y. Lu ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Body Length ◽  
Clinical Stage ◽  
Case Series ◽  
Apnea Hypopnea Index ◽  
Factors Affecting ◽  
Obstructive Sleep ◽  
Mandibular Body ◽  
Hypopnea Syndrome

Objective: To explore the feasibility, outcomes, and factors affecting the outcome of Z-palatopharyngoplasty (ZP3) in the treatment of severe obstructive sleep apnea/hypopnea syndrome (OSAHS). Study Design: Case series with chart review. Methods: ZP3 was performed on 34 Friedman stage II/III OSAHS patients with a posterior airway space (PAS) ≥ 11 mm. Postoperative follow-up was at least 6 months, and the differences between responders and nonresponders were analyzed. Results: On the basis of success criteria, defined as an apnea-hypopnea index < 20 and a decrease > 50 percent, the success rate was 64.7 percent. The lowest oxygen saturation (LSaO2), percentage of time with an oxyhemoglobin saturation below 90 percent (CT90), mandibular plane angle (MPA), mandibular body length, position of the tongue, and Friedman clinical stage differed significantly between responders and nonresponders. The logistic regression analysis showed that MPA and Friedman stage were the key predictors of ZP3 surgical success. The best cutoff points for LSaO2, CT90, and MPA were 72 percent, 22.80 percent, and 29.40°, respectively. Conclusions: Factors affecting the outcome of ZP3 included LSaO2, CT90, MPA, mandibular body length, position of the tongue, and Friedman clinical stage. Of these, the MPA and Friedman clinical stage were most influential.

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