New Internet of Medical Things for Home-Based Treatment of Anorectal Disorders

Home-based healthcare provides a viable and cost-effective method of delivery for resource- and labour-intensive therapies, such as rehabilitation therapies, including anorectal biofeedback. However, existing systems for home anorectal biofeedback are not able to monitor patient compliance or assess the quality of exercises performed, and as a result have yet to see wide spread clinical adoption. In this paper, we propose a new Internet of Medical Things (IoMT) system to provide home-based biofeedback therapy, facilitating remote monitoring by the physician. We discuss our user-centric design process and the proposed architecture, including a new sensing probe, mobile app, and cloud-based web application. A case study involving biofeedback training exercises was performed. Data from the IoMT was compared against the clinical standard, high-definition anorectal manometry. We demonstrated the feasibility of our proposed IoMT in providing anorectal pressure profiles equivalent to clinical manometry and its application for home-based anorectal biofeedback therapy.

Experimental and Numerical Study of Hygrothermal Behaviour of a Washing Fines Hemp Test Wall

Bio-based materials are a promising tracks that offer thermal and environmental performances in order to reduce the consumption of energy and of non-renewable resources. For this purpose, in a previous study, the LGCGM worked on the development of Washing Fines Hemp composites (WFH) and characterized them on multiphysical points of view. Such materials show low thermal conductivity and high moisture buffer ability. In order to characterize their hygrothermal behavior at wall scale, a test wall is set up in an air-conditioned bi-climatic test room to simulate indoor and outdoor climates. This paper investigates the characterization of hygrothermal behavior of Washing Fines Hemp wall under typical Tunisian summer climate. It consists in an experimental study, supplemented by numerical simulation performed with WUFI Pro V6.5 software. The experimental hygrothermal response of the wall to such solicitations is analyzed from the temperature and relative humidity kinetics at several positions in the wall and from temperature and vapor pressure profiles. It shows that for daily cycles the two thirds of the thickness of the wall on the exterior side are active, as well regarding heat and moisture phenomena. More sorption-desorption phenomena are highlighted. The numerical results are consistent with experimental data for temperature and underestimate vapor pressure in the inner part of the wall.

Numerical Analysis of Pressure Profiles and Energy Dissipation across Stepped Spillways Having Curved Risers

In this study, curved risers stepped spillways models based on the increasing angle of suspension were tested to check for improvement in energy dissipation and pressure distributions. Four fourteen-steps stepped spillway models with a slope 1:0.84 were selected, using Froude’s number non-dimensional similarity. The risers of steps were made curved, based on three angles of suspensions, i.e., 30°, 60°, and 90°. The simulations were performed by FLOW 3D software and by the turbulence model Renormalization Group (RNG) for discharges between 0.020 and 0.068 m3/s followed by the model calibration. The 3D Reynolds-averaged Navier–Stokes equations were solved, which included sub-grid models for air entrainment, density evaluation, and drift–flux, to capture free-surface flow over the stepped spillway. It was estimated that curving the risers increases the energy dissipation up to three percent for lower flow rates, whereas it has no significant impact on energy dissipation for higher flow rates. It was found that in simply stepped spillway lower steps dissipate more energy as compared to curved risers stepped where energy dissipation is shifted to higher steps. On the other hand, curved risers stepped spillways showed lower values of negative pressures as compared to the simply stepped spillway. It was seen that a higher energy dissipating step as experienced more negative pressures as compared to the lower energy dissipating step.

CFD MODELING OF MICROCHANNELS COOLING FOR ELECTRONIC MICRODEVICES

A simulation of the cooling of electronic devices was carried out by means of microchannels, using water as a coolant to dissipate the heat generated from a computer processor, and thus stabilize its optimum operating temperature. For the development of this study, computational fluid mechanics modeling was established in order to determine the temperature profiles, pressure profiles, and velocity behavior of the working fluid in the microchannel. In the results of the study, the operating temperatures of the computer processor were obtained, in the ranges of 303 K to 307 K, with fluid velocities in the microchannels of 5 m/s, a pressure drop of 633.7 kPa, and a factor of safety of the design of the microchannel of 15. From the results, the improvement of the heat transfer in a cooling system of electronic devices was evidenced when using a coolant as a working fluid compared to the cooling by forced air flow traditional. ABSTRAK: Simulasi penyejukan alatan elektronik telah dibina menggunakan saluran mikro, di samping air sebagai agen penyejuk bagi menghilangkan haba yang terhasil dari pemproses komputer, dan penstabil pada suhu operasi optimum. Kajian ini mengenai model komputasi mekanik bendalir bagi menentukan profil suhu, profil tekanan, dan halaju perubahan bendalir dalam saluran mikro. Dapatan kajian menunjukkan suhu operasi pemproses komputer adalah pada julat suhu 303 K sehingga 307 K, dengan halaju bendalir dalam saluran mikro adalah pada kelajuan 5 m/s, penurunan tekanan sebanyak 633.7 kPa, dan faktor keselamatan 15 bagi reka bentuk saluran mikro. Ini menunjukkan terdapat kenaikan pemindahan haba bagi sistem penyejukan alatan elektronik ini, terutama apabila cecair digunakan sebagai penyejuk haba berbanding kaedah tradisi iaitu dengan mengguna pakai aliran udara sebagai agen penyejuk.

Computational analysis of the particle size effect on the pressure profiles and type of flow regimes of TiO2 microparticles in a fluidized bed

The effect of particle size on the pressure profiles and flow regimes of the bed containing TiO2 microparticles (MPs) was investigated in a fluidized bed. The fluidization behavior of particles with mean diameters, d p , of 170, 200, 225, and 300 μm at different gas velocities, U g , was investigated both experimental and computational viewpoints. A computational fluid dynamic (CFD) model was developed by the Eulerian–Eulerian approach to evaluate the sensitivity of the Syamlal–O’Brien, and Gidaspow drag models on the predicted results of the bed pressure profiles. The results showed that with increasing particle size, the amplitude of pressure fluctuations increases and the type of flow regime in the bed tended from bubbling to slugging flow regime. The error analysis showed that the use of the Gidaspow model led to more accurate results than the Syamlal–O’Brien model in predicting the bed pressure drop and pressure fluctuations in the slugging flow regime. However, the Syamlal–O’Brien model was more suitable for predicting the pressure profiles in the bubbling flow regime. The results were more suitable for the bed containing particles of 300 μm than the beds with d p ≤ 225 μm. The highest and lowest deviations between the experimental data and simulation outputs were obtained at U g of 0.295 and 0.650 m/s, respectively. The findings confirmed that the mutual effects existed between the d p pressure profiles, and the type of flow regimes in the bed.

Modeling Transient Flow in CO2 Injection Wells by Considering the Phase Change

A transient model to simulate the temperature and pressure in CO2 injection wells is proposed and solved using the finite difference method. The model couples the variability of CO2 properties and conservation laws. The maximum error between the simulated and measured results is 5.04%. The case study shows that the phase state is primarily controlled by the wellbore temperature. Increasing the injection temperature or decreasing the injection rate contributes to obtaining the supercritical state. The variability of density can be ignored when the injection rate is low, but for a high injection rate, ignoring this may cause considerable errors in pressure profiles.

Blood pressure profiles in patients with arterial hypertension and obstructive sleep apnea in different age groups

Background. Obstructive sleep apnea (OSA) is frequently associated with hypertension (HTN), and about 50 % hypertensive patients have concomitant OSA. Episodes of transient upper airway obstruction affect the daily blood pressure profile, leading to nocturnal HTN. Although the general relationship between OSA and the daily blood pressure profile is known, the association between the frequency of various daily blood pressure profiles and OSA severity as well as the age-specific differences remain unknown. The aim of the study was to determine the daily blood pressure profiles in patients with HTN and OSA, depending on the OSA severity and age. Design and methods. The study included 236 HTN patients underwent treatment in the period from 2008 to 2021 years and were diagnosed with OSA by cardiorespiratory monitoring: 84 patients had mild OSA (apnea/hypopnea index (AHI) < 15 episodes/h), 46 patients — moderate OSA (15 ≤ AHI < 30 episodes/h), and 106 patients — severe OSA (AHI ≥ 30 episodes/h). The control group included 140 HTN patients without OSA. Both groups were divided into 3 age subgroups: younger than 45 years, 45–59 years and ≥ 60 years. At baseline, all patients underwent cardiorespiratory monitoring (“Kardiotekhnika‑07–3/12P”, Inkart, St Petersburg, Russia) and 24-hour blood pressure (BP) monitoring (BPLab, Nizhny Novgorod, Russia). Results. We found an association between the distribution of daily BP profiles and age, which differs from that in HTN patients without OSA. Non-dipper and night-peaker BP profiles are predominant in young and middle age. Among OSA patients, the severity of OSA was associated with the BP profiles only in the young and middleage groups. Unfavorable BP profiles (non-dipper and night-peaker) were more common in patients with severe OSA, which was not observed in elderly subgroup. In the elderly, compared to younger patients, the overdipper profile was the most common and its frequency was not associated with OSA severity. Conclusions. The study shows the relationship between the age of patients with HTN and OSA, the OSA severity and the distribution of daily BP profiles.

Car seat impact on driver’s sitting behavior and perceived discomfort during prolonged real driving on varied road types

Prolonged driving under real conditions can entail discomfort linked to driving posture, seat design features, and road properties like whole-body vibrations (WBV). This study evaluated the effect of three different seats (S1 = soft; S2 = firm; S3 = soft with suspension system) on driver’s sitting behavior and perceived discomfort on different road types in real driving conditions. Twenty-one participants drove the same 195 km itinerary alternating highway, city, country, and mountain segments. Throughout the driving sessions, Contact Pressure (CP), Contact Surface (CS), Seat Pressure Distribution Percentage (SPD%) and Repositioning Movements (RM) were recorded via two pressure mats installed on seat cushion and backrest. Moreover every 20 minutes, participants rated their whole-body and local discomfort. While the same increase in whole-body discomfort with driving time was observed for all three seats, S3 limited local perceived discomfort, especially in buttocks, thighs, neck, and upper back. The pressure profiles of the three seats were similar for CP, CS and RM on the backrest but differed on the seat cushion. The soft seats (S1 & S3) showed better pressure distribution, with lower SPD% than the firm seat (S2). All three showed highest CP and CS under the thighs. Road type also affected both CP and CS of all three seats, with significant differences appearing between early city, highway and country segments. In the light of these results, automotive manufacturers could enhance seat design for reduced driver discomfort by combining a soft seat cushion to reduce pressure peaks, a firm backrest to support the trunk, and a suspension system to minimize vibrations.

Numerical Analysis of an Earthen Masonry Structure Subjected to Blast Loading

Historic monuments and construction capture the knowledge of civilizations of the past and are a source of pride for people of the present. Over the centuries, these buildings have been at risk from natural and man-made causes. The Alhambra, a UNESCO World Heritage Site in Granada, Spain, is one of such places. This paper aims to evaluate the structural performance of the Torre de la Vela, a tower in the Alhambra, under blast loads. The loads were based on historical records of barrels of gunpowder and were modeled as simplified pressure profiles using existing empirical equations. The effect of impulsive loading on the material properties was accounted for using dynamic increase factors, determined experimentally by previous authors. The model was created using finite element methods (FEM) and the problem was solved using explicit dynamic analysis available in Abaqus/Explicit. Using the failure volume damage index, a blast load applied outside and inside of the building would create a low damage level, which should be treated with caution given the occurrence of localized damage. The removal of elements exceeding a given damage threshold led to more visible damage patterns than the Concrete Tension Damage option in Abaqus.