Quality Assurance and Improvement in Head and Neck Cancer Surgery: From Clinical Trials to National Healthcare Initiatives

Author(s):  
Christian Simon ◽  
Carmela Caballero
2019 ◽  
Vol 27 (2) ◽  
pp. 151-156 ◽  
Author(s):  
Christian Simon ◽  
Andreas Dietz ◽  
C. René Leemans

2021 ◽  
Vol 11 (5) ◽  
pp. 393
Author(s):  
Francesca De Felice ◽  
Daniela Musio ◽  
Vincenzo Tombolini

In head and neck cancer management, there is a need for tailored approaches to optimally implement clinical outcomes. Based on the assumption that efficacy and long-term toxicity are not satisfactory for standard concurrent platinum-based chemoradiotherapy, several trials have been designed to test whether induction immunotherapy and/or concomitant immunotherapy and radiotherapy result in improved survival and toxicity outcomes. Here, we present an overview of the most recent concomitant therapeutic strategies for head and neck cancer, focusing on the knowledge available regarding check-point inhibitors. The aim is to present the characteristics of the main check-point inhibitors and to summarize the clinical trials on the combination of immune check-point inhibitors and (chemo)radiotherapy in the definitive HNC setting, in order to provide a useful clinical tool for further research.


Oral Oncology ◽  
2016 ◽  
Vol 54 ◽  
pp. e1-e2 ◽  
Author(s):  
Massimo Del Fabbro ◽  
Sabrina Marcazzan ◽  
Sergio D’Antico ◽  
Roberto Lodovico Weinstein

2014 ◽  
Vol 272 (10) ◽  
pp. 2593-2600 ◽  
Author(s):  
Ihab Atallah ◽  
Clément Milet ◽  
Jean-Luc Coll ◽  
Emile Reyt ◽  
Christian Adrien Righini ◽  
...  

1999 ◽  
Vol 125 (9) ◽  
pp. 942 ◽  
Author(s):  
John R. Jacobs ◽  
Jerilyn Logemann ◽  
Thomas F. Pajak ◽  
Barbara Roa Pauloski ◽  
Sharon Collins ◽  
...  

2015 ◽  
Vol 152 (3) ◽  
pp. 410-417 ◽  
Author(s):  
Jeffrey C. Liu ◽  
John A. Ridge ◽  
David M. Brizel ◽  
Brian O’Sullivan ◽  
Ezra W. Cohen ◽  
...  

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