The efficacy comparison of classic ketogenic diet and modified Atkins diet in children with refractory epilepsy: a clinical trial

The modified Atkins diet is a less restrictive variation of the ketogenic diet. This diet is started on an outpatient basis without a fast, allows unlimited protein and fat, and does not restrict calories or fluids. Recent studies have shown good efficacy and tolerability of this diet in refractory epilepsy. In this review, we discuss the use of the modified Atkins diet in refractory epilepsy.

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Ketogenic diet for epilepsy treatment

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20160116 ◽

2016 ◽

Vol 74 (10) ◽

pp. 842-848 ◽

Cited By ~ 18

Author(s):

Letícia Pereira de Brito Sampaio

Keyword(s):

Ketogenic Diet ◽

Refractory Epilepsy ◽

Medium Chain Triglyceride ◽

Modified Atkins Diet ◽

The Past ◽

Atkins Diet ◽

Low Carbohydrate ◽

History Of ◽

Index Treatment ◽

Low Glycemic Index

ABSTRACT The ketogenic diet (KD), a high-fat, low-carbohydrate, and adequate-protein diet is an established, effective nonpharmacologic treatment option for intractable childhood epilepsy. The KD was developed in 1921 and even though it has been increasingly used worldwide in the past decade, many neurologists are not familiar with this therapeutic approach. In the past few years, alternative and more flexible KD variants have been developed to make the treatment easier and more palatable while reducing side effects and making it available to larger group of refractory epilepsy patients. This review summarizes the history of the KD and the principles and efficacy of the classic ketogenic diet, medium-chain triglyceride(s) (MCT) ketogenic diet, modified Atkins diet, and low glycemic index treatment.

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Treatment of refractory epilepsy. A comparison between classic ketogenic diet and modified Atkins diet in terms of efficacy, adherence, and undesirable effects

Nutrición Hospitalaria ◽

10.20960/nh.03172 ◽

2021 ◽

Author(s):

Analía Mónica Cabrera ◽

Humberto Fain ◽

Bruno Fain ◽

Julieta Muniategui ◽

Viviana María Buiras ◽

...

Keyword(s):

Ketogenic Diet ◽

Refractory Epilepsy ◽

Modified Atkins Diet ◽

Atkins Diet

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Comparison of the efficacy of classical ketogenic diet and modified Atkins diet in children and adolescents with intractable epilepsy: A non-randomized controlled clinical trial

Clinical Nutrition ◽

10.1016/j.clnu.2018.06.1967 ◽

2018 ◽

Vol 37 ◽

pp. S275-S276

Author(s):

S. Rezaei ◽

M. Kavoosi ◽

R.S. Badv ◽

M. Mohammadi ◽

G.R. Zamani ◽

...

Keyword(s):

Clinical Trial ◽

Children And Adolescents ◽

Ketogenic Diet ◽

Intractable Epilepsy ◽

Controlled Clinical Trial ◽

Randomized Controlled Clinical Trial ◽

Modified Atkins Diet ◽

Randomized Controlled ◽

Atkins Diet

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Dietary therapies for epilepsy in low resource settings: challenges and successes

Journal of the International Child Neurology Association ◽

10.17724/jicna.2021.212 ◽

2021 ◽

Vol 1 (1) ◽

Author(s):

Suvasini Sharma

Keyword(s):

Ketogenic Diet ◽

Refractory Epilepsy ◽

Low Cost ◽

Low Resource Settings ◽

Low Resource ◽

Modified Atkins Diet ◽

Atkins Diet ◽

Low Carbohydrate ◽

Drug Resistant Epilepsy ◽

Restricted Protein Diet

The Ketogenic Diet (KD) is a high fat, low carbohydrate and restricted protein diet which has been used for the treatment of drug resistant epilepsy in children. It is considered the treatment of choice for refractory nonsurgical epilepsy in children. However, despite this being a very useful and relatively simple treatment, children from developing countries have not been able to benefit as much as their counterparts in more privileged settings. In this article, the challenges faced by pediatric neurologists and parents who wish to use the diet in children with refractory epilepsy are discussed, and also the simple low cost innovations which can be used to overcome these challenges are suggested. The evolution from the use of the classic ketogenic diet to the flexible use of the modified Atkins diet in low resource settings will be discussed.

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