scholarly journals COVID-19 in a kidney transplant recipient treated with eculizumab for atypical hemolytic uremic syndrome: a case report

Author(s):  
Noëlle Cognard ◽  
Gabriela Gautier-Vargas ◽  
Peggy Perrin ◽  
Ilies Benotmane ◽  
Sophie Caillard
Author(s):  
John Fredy Nieto-Rios ◽  
Monica Zuluaga-Quintero ◽  
Julio Cesar Valencia-Maturana ◽  
Diana Carolina Bello-Marquez ◽  
Arbey Aristizabal-Alzate ◽  
...  

Abstract Thrombotic microangiopathies are disorders characterized by nonimmune microangiopathic hemolytic anemia, thrombocytopenia, and multi-systemic failure. They are classified as thrombotic thrombocytopenic purpura, atypical hemolytic-uremic syndrome, and typical hemolytic uremic syndrome. The latter is associated with intestinal infections by Shiga toxin-producing bacteria. Typical hemolytic uremic syndrome in adults is an extremely rare condition, characterized by high morbidity and mortality. It has been seldom described in solid organ transplant recipients. Here is presented the case of a kidney transplant recipient who had typical hemolytic uremic syndrome with multisystem commitment, refractory to management and with a fatal outcome.


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