Eculizumab and Belatacept for De Novo Atypical Hemolytic Uremic Syndrome Associated With CFHR3-CFHR1 Deletion in a Kidney Transplant Recipient: A Case Report

2017 ◽  
Vol 49 (1) ◽  
pp. 188-192 ◽  
Author(s):  
P. Dedhia ◽  
A. Govil ◽  
G. Mogilishetty ◽  
R.R. Alloway ◽  
E.S. Woodle ◽  
...  
Author(s):  
John Fredy Nieto-Rios ◽  
Monica Zuluaga-Quintero ◽  
Julio Cesar Valencia-Maturana ◽  
Diana Carolina Bello-Marquez ◽  
Arbey Aristizabal-Alzate ◽  
...  

Abstract Thrombotic microangiopathies are disorders characterized by nonimmune microangiopathic hemolytic anemia, thrombocytopenia, and multi-systemic failure. They are classified as thrombotic thrombocytopenic purpura, atypical hemolytic-uremic syndrome, and typical hemolytic uremic syndrome. The latter is associated with intestinal infections by Shiga toxin-producing bacteria. Typical hemolytic uremic syndrome in adults is an extremely rare condition, characterized by high morbidity and mortality. It has been seldom described in solid organ transplant recipients. Here is presented the case of a kidney transplant recipient who had typical hemolytic uremic syndrome with multisystem commitment, refractory to management and with a fatal outcome.


2016 ◽  
Vol 10 (1) ◽  
pp. 30-32
Author(s):  
Amina Izem ◽  
Béfa Noto-Kadou-Kaza ◽  
Kawtar Mabrouk ◽  
Naoufal Mtiou ◽  
Kossi Akomola Sabi ◽  
...  

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