Prediction of sudden death from QTc prolongation in a medical cohort with coronary artery disease

1982 ◽  
Vol 49 (4) ◽  
pp. 1006 ◽  
Author(s):  
Paolo E. Puddu ◽  
Martial G. Bourassa
2021 ◽  
Vol 77 (1) ◽  
pp. 29-41
Author(s):  
Abbasin Zegard ◽  
Osita Okafor ◽  
Joseph de Bono ◽  
Manish Kalla ◽  
Mauro Lencioni ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dong-Hyuk Cho ◽  
Jimi Choi ◽  
Mi-Na Kim ◽  
Hee-Dong Kim ◽  
Soon Jun Hong ◽  
...  

AbstractIdentification of obstructive coronary artery disease (OCAD) in patients with chest pain is a clinical challenge. The value of corrected QT interval (QTc) for the prediction of OCAD has yet to be established. We consecutively enrolled 1741 patients with suspected angina. The presence of obstructive OCAD was defined as ≥ 50% diameter stenosis by coronary angiography. The pre-test probability was evaluated by combining QTc prolongation with the CAD Consortium clinical score (CAD2) and the updated Diamond-Forrester (UDF) score. OCAD was detected in 661 patients (38.0%). QTc was longer in patients with OCAD compared with those without OCAD (444 ± 34 vs. 429 ± 28 ms, p < 0.001). QTc was increased by the severity of OCAD (P < 0.001). QTc prolongation was associated with OCAD (odds ratio (OR), 2.27; 95% confidence interval (CI), 1.81–2.85). With QTc, the C-statistics increased significantly from 0.68 (95% CI 0.66–0.71) to 0.76 (95% CI 0.74–0.78) in the CAD2 and from 0.64 (95% CI 0.62–0.67) to 0.74 (95% CI 0.72–0.77) in the UDF score, respectively. QT prolongation predicted the presence of OCAD and the QTc improved model performance to predict OCAD compared with CAD2 or UDF scores in patients with suspected angina.


1977 ◽  
Vol 39 (6) ◽  
pp. 821-828 ◽  
Author(s):  
Louis A. Vismara ◽  
Zakauddin Vera ◽  
James M. Foerster ◽  
Ezra A. Amsterdam ◽  
Dean T. Mason

1994 ◽  
Vol 74 (8) ◽  
pp. 743-747 ◽  
Author(s):  
Richard D. Lane ◽  
Anthony C. Caruso ◽  
Victoria L. Brown ◽  
Beatrice Axelrod ◽  
Gary E. Schwartz ◽  
...  

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