Structure-activity relationships in the destruction of cytochrome P-450 mediated by certain ethynyl-substituted compounds in rats

Biochemical Pharmacology ◽

10.1016/0006-2952(80)90299-3 ◽

1980 ◽

Vol 29 (24) ◽

pp. 3253-3255 ◽

Author(s):

Ian N.H. White

Keyword(s):

Structure Activity Relationships ◽

Structure Activity ◽

Cytochrome P 450

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Immunochemical quantitation of cytochrome P-450 isozymes and epoxide hydrolase in liver microsomes from polychlorinated or polybrominated biphenyl-treated rats. A study of structure-activity relationships.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)81991-7 ◽

1983 ◽

Vol 258 (9) ◽

pp. 5967-5976

Author(s):

A Parkinson ◽

S H Safe ◽

L W Robertson ◽

P E Thomas ◽

D E Ryan ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Liver Microsomes ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunochemical Quantitation ◽

Polybrominated Biphenyl ◽

Cytochrome P 450

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Influence of Various Estrogens on Biotransformation: Affinity to Cytochrome P-450, Structure Activity Relationships, and Scavenger Function

Archiv der Pharmazie ◽

10.1002/ardp.19973300505 ◽

1997 ◽

Vol 330 (5) ◽

pp. 135-140

Author(s):

Sabine Gernhardt ◽

Elke Karge ◽

Bruno Schönecker ◽

Wolfgang Klinger

Keyword(s):

Structure Activity Relationships ◽

Structure Activity ◽

Cytochrome P 450

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Structure—activity relationships on cytochrome P-450 LM2

Journal of Molecular Structure THEOCHEM ◽

10.1016/0166-1280(88)80061-7 ◽

1988 ◽

Vol 170 ◽

pp. 181-187 ◽

Author(s):

J. Jäger ◽

W. Schwarze ◽

K. Ruckpaul

Keyword(s):

Structure Activity Relationships ◽

Structure Activity ◽

Cytochrome P 450

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The structure—activity relationships of flavonoids as inhibitors of cytochrome P-450 enzymes in rat liver microsomes and the mutagenicity of 2-amino-3-methyl-imidazo[4,5-f]quinoline

Mutagenesis ◽

10.1093/mutage/9.2.101 ◽

1994 ◽

Vol 9 (2) ◽

pp. 101-106 ◽

Author(s):

Huei Lee ◽

Hui-Wu Wang ◽

Hsueh-Yueh Su ◽

Nina Jyu Hao

Keyword(s):

Rat Liver ◽

Liver Microsomes ◽

Rat Liver Microsomes ◽

Structure Activity Relationships ◽

Structure Activity ◽

Cytochrome P 450

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Quantitative structure-activity relationships in a series of alcohols exhibiting inhibition of cytochrome P-450-mediated aniline hydroxylation

Chemico-Biological Interactions ◽

10.1016/0009-2797(87)90027-5 ◽

1987 ◽

Vol 62 (3) ◽

pp. 271-280 ◽

Author(s):

David F.V. Lewis

Keyword(s):

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Cytochrome P 450

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Quantitative structure—Activity relationships in a series of urea derivatives—Liver cytochrome P-450 inductors analyzed by the modified method of frontal polyhedra

Pharmaceutical Chemistry Journal ◽

10.1007/bf02464126 ◽

1997 ◽

Vol 31 (6) ◽

pp. 320-325

Author(s):

A. I. Khlebnikov ◽

A. A. Bakibaev ◽

R. R. Akhmedzhanov ◽

T. P. Novozheeva ◽

A. S. Saratikov

Keyword(s):

Quantitative Structure ◽

Urea Derivatives ◽

Structure Activity Relationships ◽

Liver Cytochrome ◽

Modified Method ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Cytochrome P 450

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Quantitative Structure-Activity Relationships of Cytochrome P-450

Drug Metabolism Reviews ◽

10.3109/03602539308993972 ◽

1993 ◽

Vol 25 (1-2) ◽

pp. 1-48 ◽

Author(s):

Corwin Hansch ◽

Litai Zhang

Keyword(s):

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Cytochrome P 450

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Structure-activity relationships of chlorinated benzenes as inducers of different forms of cytochrome P-450 in rat liver

Chemico-Biological Interactions ◽

10.1016/0009-2797(82)90084-9 ◽

1982 ◽

Vol 41 (2) ◽

pp. 131-139 ◽

Author(s):

J.A. Goldstein ◽

P. Linko ◽

J.N. Huckins ◽

D.L. Stalling

Keyword(s):

Rat Liver ◽

Chlorinated Benzenes ◽

Structure Activity Relationships ◽

Structure Activity ◽

Cytochrome P 450

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Effects of individual terphenyls and polychlorinated terphenyls on rat hepatic microsomal cytochrome P-450-dependent monooxygenases: structure-activity relationships

Archives of Toxicology ◽

10.1007/bf00316331 ◽

1986 ◽

Vol 59 (3) ◽

pp. 186-189 ◽

Author(s):

B. D. Leece ◽

M. A. Denomme ◽

S. M. A. Li ◽

R. A. Towner ◽

J. W. Gyorkos ◽

...

Keyword(s):

Microsomal Cytochrome ◽

Structure Activity Relationships ◽

Structure Activity ◽

Cytochrome P 450

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Inhibition of hepatic drug metabolism by phenothiazine tranquilizers: quantitative structure-activity relationships and selective inhibition of cytochrome P-450 isoform-specific activities

Chemical Research in Toxicology ◽

10.1021/tx00010a005 ◽

1989 ◽

Vol 2 (4) ◽

pp. 240-246 ◽

Author(s):

Michael Murray

Keyword(s):

Drug Metabolism ◽

Selective Inhibition ◽

Hepatic Drug Metabolism ◽

Quantitative Structure ◽

Hepatic Drug ◽

Structure Activity Relationships ◽

Structure Activity ◽

Specific Activities ◽

Quantitative Structure Activity Relationships ◽

Cytochrome P 450

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