The inhibition of glycine and β-methylglucoside transport in dog kidney cortex slices by ouabain and ethacrynic acid: Contribution to the understanding of sodium-pumping mechanisms

1972 ◽  
Vol 3 (10) ◽  
pp. 145-159 ◽  
Author(s):  
J.W.L. Robinson
Keyword(s):  
Ethacrynic Acid ◽  
Kidney Cortex ◽  
Dog Kidney ◽  
Sodium Pumping ◽  
Cortex Slices ◽  
Kidney Cortex Slices

Tamm—Horsfall Glycoprotein Release from Rat Kidney Cortex Slices in Vitro

1984 ◽  
Vol 67 (5) ◽  
pp. 529-534 ◽  
Author(s):  
P. K. Wirdnam ◽  
R. D. G. Milner
Keyword(s):  
Cell Membrane ◽  
Ethacrynic Acid ◽  
Rat Kidney ◽  
Kidney Cortex ◽  
Rat Kidney Cortex ◽  
The Media ◽  
Cortex Slices ◽  
Kidney Cortex Slices ◽  
Krebs Henseleit Buffer

1. Rat kidney cortex slices were incubated for 30 min at 37°C in unmodified Krebs-Henseleit buffer containing aldosterone, vasopressin, theophylline, ethacrynic acid, frusemide, spironolactone or ouabain. 2. Tamm—Horsfall glycoprotein (THG) released into the media was measured by radioimmunoassay and at the end of each experiment the slices were homogenized and assayed for THG content. 3. Incubation of kidney cortex slices in unmodified buffer resulted in a significant increase in the slice THG content when compared with pre-incubation levels. The increase was prevented by puromycin or cycloheximide. 4. Incubation in ethacrynic acid (1 mmol/l) or frusemide (10 mmol/l) resulted in a significant increase in release of THG when compared with unmodified buffer. Puromycin or cycloheximide failed to prevent the increased release. 5. THG release induced by ethacrynic acid or frusemide is probably the result of an aggregation-disaggregation reaction on the cell membrane. It is suggested that the action of the chloride inhibiting diuretics, ethacrynic acid and frusemide, is mediated in some way via THG.

scholarly journals RELEASE OF RENIN FROM DOG KIDNEY CORTEX SLICES IN VITRO

1967 ◽  
Vol 17 (4) ◽  
pp. 685-686 ◽  
Author(s):  
KENJIRO YAMAMOTO ◽  
HIROSHI TANAKA ◽  
KUNISUKE HORIUCHI ◽  
JURO UEDA
Keyword(s):  
Kidney Cortex ◽  
Dog Kidney ◽  
Cortex Slices ◽  
Kidney Cortex Slices

scholarly journals RELEASE OF RENIN FROM DOG KIDNEY CORTEX SLICES IN VITRO

1967 ◽  
Vol 17 (4) ◽  
pp. 685-686
Author(s):  
KENJIRO YAMAMOTO ◽  
HIROSHI TANAKA ◽  
KUNISUKE HORIUCHI ◽  
JURO UEDA
Keyword(s):  
Kidney Cortex ◽  
Dog Kidney ◽  
Cortex Slices ◽  
Kidney Cortex Slices

scholarly journals A RELEASE OF RENIN FROM DOG KIDNEY CORTEX SLICES

1970 ◽  
Vol 20 (4) ◽  
pp. 586-595 ◽  
Author(s):  
SHIRO MORIMOTO ◽  
KENJIRO YAMAMOTO ◽  
KUNISUKE HORIUCHI ◽  
HIROSHI TANAKA ◽  
JURO UEDA
Keyword(s):  
Kidney Cortex ◽  
Dog Kidney ◽  
Cortex Slices ◽  
Kidney Cortex Slices
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