scholarly journals Comparison of the visually evoked response in drug-free chronic schizophrenic patients and normal controls

1979 ◽  
Vol 46 (2) ◽  
pp. 123-137 ◽  
Author(s):  
Edward F Domino ◽  
Sandra Demetriou ◽  
Thomas Tuttle ◽  
Valerie Klinge
Keyword(s):  
Evoked Response ◽  
Chronic Schizophrenic ◽  
Schizophrenic Patients ◽  
Drug Free ◽  
Normal Controls

Negative Features, Retrieval Processes and Verbal Fluency in Schizophrenia

1993 ◽  
Vol 163 (6) ◽  
pp. 769-775 ◽  
Author(s):  
Heidi A. Allen ◽  
Peter F. Liddle ◽  
Christopher D. Frith
Keyword(s):  
Verbal Fluency ◽  
Chronic Schizophrenic ◽  
Retrieval Processes ◽  
Schizophrenic Patients ◽  
Normal Controls

Twenty chronic schizophrenic patients, ten matched normal controls and nine depressed controls performed categorical verbal fluency tasks for three minutes each on five separate occasions. On each occasion the schizophrenic patients generated significantly fewer words than the controls. Comparison of the different occasions showed that the schizophrenic patients had as many words available in their inner lexicons but were inefficient in retrieving them. The schizophrenic patients also generated fewer clusters of related words and more words outside the specified category. Reduced ability to generate words while the lexicon remained intact was more marked in patients with negative features. Patients with incoherence, in contrast, were more likely to produce inappropriate words. We propose that both poverty of speech and incoherence of speech reflect problems in the retrieval of words from the lexicon. To cope with these problems patients with poverty of speech terminate their search prematurely while the patients with incoherence commit errors in selecting words for output.

Early antipsychotic response to resumption of neuroleptics in drug-free chronic schizophrenic patients

1992 ◽  
Vol 31 (9) ◽  
pp. 968-970 ◽  
Author(s):  
David Glovinsky ◽  
Darrell G. Kirch ◽  
Richard Jed Wyatt
Keyword(s):  
Chronic Schizophrenic ◽  
Schizophrenic Patients ◽  
Drug Free

Aberrant interhemispheric alpha coherence on electroencephalography in schizophrenic patients during activation tasks

1996 ◽  
Vol 26 (3) ◽  
pp. 605-612 ◽  
Author(s):  
S. L. Morrison-Stewart ◽  
D. Velikonja ◽  
W. C. Corning ◽  
P. Williamson
Keyword(s):  
Right Hemisphere ◽  
Functional Organization ◽  
Normal Subjects ◽  
Brain Regions ◽  
Interhemispheric Coherence ◽  
Schizophrenic Patients ◽  
Coherence Patterns ◽  
Drug Free ◽  
The Brain ◽  
Normal Controls

SynopsisThirty schizophrenic patients (20 medicated, 10 off medication) were compared with 30 normal controls subjects matched for age, sex, handedness and intelligence. During the performance of a frontal activation task, normal subjects showed increased interhemispheric coherence between anterior brain regions. Schizophrenic patients did not show the same amount of bilateral anterior activation. During the performance of right hemisphere cognitive activation tasks, normal subjects and medicated schizophrenic patients showed significantly reduced bilateral interhemispheric coherence patterns, while the drug-free schizophrenic patients showed a trend towards this same pattern. It is suggested that these findings provide additional evidence for an aberrant functional organization of the brain in schizophrenia.

Artificial Organs: Thoughts & Progress:Plasma β-Endorphin Levels In Chronic Schizophrenic Patients and Normal Controls

2008 ◽  
Vol 3 (4) ◽  
pp. 375-377
Author(s):  
Enrique Espinosa-Meléndez ◽  
Samarthju Lal ◽  
N. P. Vasavan Nair ◽  
Thomas Ming Swi Chang
Keyword(s):  
Artificial Organs ◽  
Chronic Schizophrenic ◽  
Schizophrenic Patients ◽  
Normal Controls

The cognitive effects of ketamine, an NMDA antagonist, in normal controls and drug-free schizophrenic patients

1995 ◽  
Vol 15 (1-2) ◽  
pp. 158
Author(s):  
A.K. Malhotra ◽  
H. Weingartner ◽  
K. Sirocco ◽  
D. Pinals ◽  
C.D. Missar ◽  
...  
Keyword(s):  
Nmda Antagonist ◽  
Cognitive Effects ◽  
Schizophrenic Patients ◽  
Drug Free ◽  
Normal Controls

Serum Calcium and Magnesium in Schizophrenia: Relationship to Clinical Phenomena and Neuroleptic Treatment

1978 ◽  
Vol 133 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Paul E. Alexander ◽  
Daniel P. van Kammen ◽  
William E. Bunney
Keyword(s):  
Serum Calcium ◽  
Neuroleptic Drug ◽  
Neuroleptic Treatment ◽  
Schizophrenic Patients ◽  
Calcium And Magnesium ◽  
Drug Free ◽  
Neuroleptic Withdrawal ◽  
Similar Decrease ◽  
Normal Controls

SummarySerum calcium and magnesium were studied in drug-free and neuroleptic-treated schizophrenic patients. Calcium and magnesium were not significantly different in 31 unmedicated schizophrenic patients compared with normal controls. Serum calcium was altered, however, in two subgroups: (1) Patients who remitted after neuroleptic withdrawal were significantly lower in calcium than those who did not remit; (2) catatonic schizophrenic patients appeared to have an increased calcium at the onset of catatonic stupor.Patients treated with pimozide were found to have a significant decrease in both calcium and magnesium compared with their drug-free values. These same patients showed a similar decrease in both electrolytes during treatment with fluphenazine, a structurally different neuroleptic drug.

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