Modelling compound action potentials of peripheral nerves in situ. I. Model description; evidence for a non-linear relation between fibre diameter and velocity

1982 ◽  
Vol 54 (4) ◽  
pp. 436-448 ◽  
Author(s):  
D.F Stegeman ◽  
J.P.C De Weerd
Keyword(s):  
Linear Relation ◽  
Peripheral Nerves ◽  
Action Potentials ◽  
Fibre Diameter ◽  
Model Description ◽  
Non Linear ◽  
Compound Action Potentials ◽  
Compound Action

scholarly journals Effects of Photodynamic Therapy on Peripheral Nerve: In Situ Compound-Action Potentials Study in a Canine Model

2005 ◽  
Vol 23 (2) ◽  
pp. 172-176 ◽  
Author(s):  
Kenneth C. Dole ◽  
Qun Chen ◽  
Fred W. Hetzel ◽  
Lawrence R. Whalen ◽  
Dominique Blanc ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Peripheral Nerve ◽  
Action Potentials ◽  
Canine Model ◽  
Compound Action Potentials ◽  
Compound Action

scholarly journals A wrappable microwire electrode for awake, chronic interfacing with small diameter autonomic peripheral nerves

2018 ◽  
Author(s):  
Jessica D. Falcone ◽  
Tristan Liu ◽  
Laura Goldman ◽  
David D. Pogue ◽  
Malgorzata Straka ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Peripheral Nerves ◽  
Action Potentials ◽  
Small Diameter ◽  
Preclinical Model ◽  
Preclinical Models ◽  
Acute Setting ◽  
Bioelectronic Medicine ◽  
Compound Action Potentials ◽  
Compound Action

Bioelectronic medicine requires the ability to monitor and modulate nerve activity in awake patients over time. The vagus nerve is a promising stimulation target, and preclinical models often use mice. However, an awake, chronic mouse vagus nerve interface has yet to be demonstrated. Here, we developed a functional wrappable microwire electrode to chronically interface with the small diameter mouse cervical vagus nerve (∼100 μm). In an acute setting, the wrappable microwire had similar recording performance to commercially available electrodes. A chronic, awake mouse model was then developed to record spontaneous compound action potentials (CAPs). Viable signal-to-noise ratios (SNRs) were obtained from the wrappable microwires between 30 and 60 days (n = 8). Weekly impedance measurements showed no correlation between SNR or time. The wrappable microwires successfully interfaced with small diameter nerves and has been validated in a chronic, awake preclinical model, which can better facilitate clinical translation for bioelectronic medicine.

scholarly journals Compound action potentials recorded from mammalian peripheral nerves following ligation or resuturing.

1978 ◽  
Vol 285 (1) ◽  
pp. 543-559 ◽  
Author(s):  
L A Davis ◽  
T Gordon ◽  
J A Hoffer ◽  
J Jhamandas ◽  
R B Stein
Keyword(s):  
Peripheral Nerves ◽  
Action Potentials ◽  
Compound Action Potentials ◽  
Compound Action

scholarly journals Direct Opioid Application to Peripheral Nerves Does Not Alter Compound Action Potentials

1985 ◽  
Vol 64 (7) ◽  
pp. 667???671 ◽  
Author(s):  
Osafumi Yuge ◽  
Maki Matsumoto ◽  
Luke M. Kitahata ◽  
J. G. Collins ◽  
Mesaki Senami
Keyword(s):  
Peripheral Nerves ◽  
Action Potentials ◽  
Compound Action Potentials ◽  
Compound Action

Stretch of mammalian nerve in vitro: Effect on compound action potentials

2000 ◽  
Vol 5 (4) ◽  
pp. 227-235 ◽  
Author(s):  
Sidney Ochs ◽  
Rahman Pourmand ◽  
Kenan Si ◽  
Richard N. Friedman
Keyword(s):  
Action Potentials ◽  
Compound Action Potentials ◽  
Vitro Effect ◽  
Mammalian Nerve ◽  
Compound Action

scholarly journals Site of cochlear stimulation and its effect on electrically evoked compound action potentials using the MED-EL standard electrode array

2009 ◽  
Vol 8 (1) ◽  
pp. 40 ◽  
Author(s):  
Stefan Brill ◽  
Joachim Müller ◽  
Rudolf Hagen ◽  
Alexander Möltner ◽  
Steffi-Johanna Brockmeier ◽  
...  
Keyword(s):  
Action Potentials ◽  
Electrode Array ◽  
Compound Action Potentials ◽  
Compound Action
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