Specific detection of Haemophilus influenzae type b lipooligosaccharide by a polymyxin B monoclonal antibody assay

1989 ◽  
Vol 122 (2) ◽  
pp. 219-226 ◽  
Author(s):  
Jussi Mertsola ◽  
Octavio Ramilo ◽  
Xavier Sáez-Llorens ◽  
Mark S. Hanson ◽  
George H. McCracken ◽  
...  
1993 ◽  
Vol 110 (2) ◽  
pp. 307-316 ◽  
Author(s):  
M. A. M. Salih ◽  
H. Fredlund ◽  
S. Hugosson ◽  
L. Bodin ◽  
P. Olcén

SUMMARYSampling of sera from 202 Sudanese and 124 Swedish children 1–14 years of age was conducted at the end of the 1980s presenting an opportunity to compare the seroprevalence of anti-Neisseria meningitidis (MC) serogroup A antibodies in an area immediately before outbreak of an epidemic (Sudan 1988) with a low endemic area (Sweden). An ELISA antibody assay was developed for detection of antibodies against capsular polysaccharide of MC serogroup A and Haemophilus influenzae type b (Hib). Serum antibody against MC serogroup A was found significantly more frequently in Sudanese than in Swedish children. This indicates that factors other than herd immunity, as measured by serum antibodies against MC serogroup A polysaccharide, are important for avoidance of an MC serogroup A epidemic. The seroprevalence of Hib antibodies was, in contrast, significantly higher in Swedish than in Sudanese children, especially for 5–9-year-old children. A possible explanation may be the different systems of day-care of children in the two countries.


1987 ◽  
Vol 25 (12) ◽  
pp. 2434-2436 ◽  
Author(s):  
J Hamel ◽  
B R Brodeur ◽  
A Belmaaza ◽  
S Montplaisir ◽  
J M Musser ◽  
...  

1990 ◽  
Vol 28 (12) ◽  
pp. 2700-2706 ◽  
Author(s):  
J Mertsola ◽  
R S Munford ◽  
O Ramilo ◽  
X Sáez-Llorens ◽  
M M Mustafa ◽  
...  

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