Specific interaction of corticosteroids with components of the cell membrane which are involved in the translocation of the hormone into the intravesicular space of purified rat liver plasma membrane vesicles

1980 ◽  
Vol 12 ◽  
pp. 259-266 ◽  
Author(s):  
Axel Alléra ◽  
Govind S. Rao ◽  
Heinz Breuer
Keyword(s):  
Plasma Membrane ◽  
Cell Membrane ◽  
Rat Liver ◽  
Specific Interaction ◽  
Membrane Vesicles ◽  
Plasma Membrane Vesicles ◽  
Liver Plasma Membrane

Thiamine transport by basolateral rat liver plasma membrane vesicles

1992 ◽  
Vol 103 (3) ◽  
pp. 1056-1065 ◽  
Author(s):  
Richard H. Moseley ◽  
Pankaj G. Vashi ◽  
Suzanne M. Jarose ◽  
Chris J. Dickinson ◽  
Patricia A. Permoad
Keyword(s):  
Plasma Membrane ◽  
Rat Liver ◽  
Membrane Vesicles ◽  
Plasma Membrane Vesicles ◽  
Liver Plasma Membrane ◽  
Thiamine Transport

scholarly journals Evidence for carrier-mediated chloride/bicarbonate exchange in canalicular rat liver plasma membrane vesicles.

1985 ◽  
Vol 75 (4) ◽  
pp. 1256-1263 ◽  
Author(s):  
P J Meier ◽  
R Knickelbein ◽  
R H Moseley ◽  
J W Dobbins ◽  
J L Boyer
Keyword(s):  
Plasma Membrane ◽  
Rat Liver ◽  
Membrane Vesicles ◽  
Plasma Membrane Vesicles ◽  
Liver Plasma Membrane

Multispecific anion exchange in basolateral (sinusoidal) rat liver plasma membrane vesicles

1986 ◽  
Vol 251 (5) ◽  
pp. G656-G664 ◽  
Author(s):  
G. Hugentobler ◽  
P. J. Meier
Keyword(s):  
Plasma Membrane ◽  
Rat Liver ◽  
Driving Forces ◽  
Competitive Inhibition ◽  
Membrane Vesicles ◽  
Ph Gradient ◽  
Disulfonic Acid ◽  
Sulfate Uptake ◽  
Plasma Membrane Vesicles ◽  
Liver Plasma Membrane

The mechanisms and driving forces for hepatic uptake of sulfate were investigated in basolateral (sinusoidal) rat liver plasma membrane vesicles. A transmembrane pH difference (pH 8.0 inside, 6.0 outside) stimulated sulfate uptake above equilibrium (“overshoot”). This pH gradient-stimulated sulfate uptake was saturable with increasing concentrations of sulfate and could be inhibited by probenecid, 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS), carbonyl cyanide p-(trifluoromethoxy)-phenylhydrazone, and nigericin. At low buffer concentrations and pH 6.0 an inwardly directed sodium gradient also stimulated sulfate uptake. This sodium-dependent sulfate uptake could be inhibited by amiloride and DIDS, indicating indirect coupling of sodium and sulfate flux through concomitant sodium-proton and sulfate-hydroxyl exchange. Cisinhibition of initial pH gradient-stimulated sulfate uptake, as well as transstimulation of sulfate uptake under pH-equilibrated conditions (pH 7.5 inside and outside), were observed with sulfate, thiosulfate, oxalate, and succinate, but not with chloride, bicarbonate, acetate, lactate, pyruvate, p-aminohippurate, citrate, glutamate, aspartate, and taurocholate. Furthermore, cholate and sulfobromophthalein exhibited competitive inhibition of pH gradient-stimulated sulfate uptake. In addition, an inside-to-outside hydroxyl gradient also stimulated uptake of cholate and this pH gradient-sensitive portion of cholate uptake was inhibited by extravesicular sulfate. In contrast to basolateral membranes, no evidence for multispecific sulfate-hydroxyl exchange was found in canalicular plasma membrane vesicles.

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