621 Double-blind study of the effectiveness of a high-efficiency particulate air (HEPA) filter in patients with perennial allergic rhinitis and asthma

SummaryThe object of this double-blind study was to assess the therapeutic effects of a combination of two per cent sodium cromoglycate and 0.025 per cent xylometazoline compared with a matched placebo. Forty patients were included in the two-week study.The treatment was found to be rapidly effective taking only a day to control symptoms in almost 80 per cent of the patients in the group receiving active treatment.No evidence of rebound effects due to the decongestant was observed during the study.

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Comparative Multicentric Double-Blind Study between Dexchlorpheniramine and Astemizole in the Treatment of Children with Perennial Allergic Rhinitis

American Journal of Rhinology ◽

10.2500/105065890782009460 ◽

1990 ◽

Vol 4 (3) ◽

pp. 109-114

Author(s):

Charles K. Naspitz ◽

Dirceu Sal&eacute ◽

Neusa F. Wandalsen ◽

Evandro Prado ◽

Nelson Rosario Filho ◽

...

Keyword(s):

Allergic Rhinitis ◽

Blind Study ◽

Double Blind Study ◽

Perennial Allergic Rhinitis ◽

Double Blind

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Faculty of 1000 evaluation for Tap water nasal irrigation in adults with seasonal allergic rhinitis: a randomized double-blind study.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.718131891.793486407 ◽

2013 ◽

Author(s):

Zachary Soler

Keyword(s):

Allergic Rhinitis ◽

Seasonal Allergic Rhinitis ◽

Tap Water ◽

Blind Study ◽

Double Blind Study ◽

Double Blind ◽

Nasal Irrigation

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A Parallel-Group Comparison of Astemizole and Loratadine for the Treatment of Perennial Allergic Rhinitis

Journal of International Medical Research ◽

10.1177/030006059702500401 ◽

1997 ◽

Vol 25 (4) ◽

pp. 175-181 ◽

Cited By ~ 66

Author(s):

H Al-Muhaimeed

Keyword(s):

Allergic Rhinitis ◽

Statistical Significance ◽

Double Blind Study ◽

Perennial Allergic Rhinitis ◽

Double Blind ◽

Once Daily ◽

Runny Nose ◽

Parallel Group ◽

The Mean ◽

To Receive

The efficacy and safety of the two antihistamines, astemizole and loratadine, were compared in a double-blind study of 84 patients with perennial allergic rhinitis. Patients were randomized to receive orally either astemizole 10 mg once daily ( n = 40) or loratadine 10 mg once daily ( n = 44) for 1 week. No other antirhinitis medication was allowed during the study. By day 7 the mean daily symptom scores, recorded on diary cards, were lower in patients receiving astemizole than in those receiving loratadine for runny nose, itchy nose and sneezing, although not for blocked nose, and treatment differences only reached statistical significance for runny nose. After 7 days, 53.75% of patients on astemizole and 38.6% on loratadine were free of symptoms, and 87% of patients on astemizole described the treatment as good or excellent compared with 62% on loratadine. The present results suggest that astemizole may be more effective than loratadine in controlling symptoms of perennial allergic rhinitis.

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