A primary culture system of postnatal rat heart cells for the study of cocaine and methamphetamine toxicity

1992 ◽  
Vol 60 (2) ◽  
pp. 183-196 ◽  
Author(s):  
Allison Anne Welder
Keyword(s):  
Primary Culture ◽  
Rat Heart ◽  
Culture System ◽  
Heart Cells ◽  
Rat Heart Cells

A primary culture system of adult rat heart cells for the study of toxicologic agents

1991 ◽  
Vol 27 (12) ◽  
pp. 921-926 ◽  
Author(s):  
Allison A. Welder ◽  
Roberta Grant ◽  
June Bradlaw ◽  
Daniel Acosta
Keyword(s):  
Primary Culture ◽  
Rat Heart ◽  
Culture System ◽  
Heart Cells ◽  
Adult Rat ◽  
Rat Heart Cells

scholarly journals Characterization of a strong positive cis-acting element of the human beta-myosin heavy chain gene in fetal rat heart cells.

1992 ◽  
Vol 267 (14) ◽  
pp. 9917-9924 ◽  
Author(s):  
I.L. Flink ◽  
J.G. Edwards ◽  
J.J. Bahl ◽  
C.C. Liew ◽  
M Sole ◽  
...  
Keyword(s):  
Heavy Chain ◽  
Rat Heart ◽  
Chain Gene ◽  
Heart Cells ◽  
Heavy Chain Gene ◽  
Myosin Heavy Chain Gene ◽  
Cis Acting ◽  
Fetal Rat ◽  
Rat Heart Cells

Plasma from cirrhotic patients induces inotropic changes on cultured rat heart cells

Life Sciences ◽  
1987 ◽  
Vol 41 (19) ◽  
pp. 2177-2184 ◽  
Author(s):  
Lidia E.P. de Mikulic ◽  
Marie-Claude Auclair ◽  
Catherine Vernimmen ◽  
Didier Lebrec ◽  
Esteban Mikulic
Keyword(s):  
Rat Heart ◽  
Heart Cells ◽  
Cirrhotic Patients ◽  
Rat Heart Cells

scholarly journals EFFECTS OF CORTISOL ON CULTURED RAT HEART CELLS

1973 ◽  
Vol 57 (1) ◽  
pp. 109-116 ◽  
Author(s):  
J. V. Anastasia ◽  
R. L. McCarl
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Free Fatty Acids ◽  
Fatty Acid Oxidation ◽  
Growth Medium ◽  
Rat Heart ◽  
Acid Oxidation ◽  
Heart Cells ◽  
Atp Production ◽  
Rat Heart Cells

This paper reports the determination of the ability of rat heart cells in culture to release [14C]palmitate from its triglyceride and to oxidize this fatty acid and free [14C]palmitate to 14CO2 when the cells are actively beating and when they stop beating after aging in culture. In addition, the levels of glucose, glycogen, and ATP were determined to relate the concentration of these metabolites with beating and with cessation of beating. When young rat heart cells in culture are actively beating, they oxidize free fatty acids at a rate parallel with cellular ATP production. Both fatty acid oxidation and ATP production remain constant while the cells continue to beat. Furthermore, glucose is removed from the growth medium by the cells and stored as glycogen. When cultured cells stop beating, a decrease is seen in their ability to oxidize free fatty acids and to release them from their corresponding triglycerides. Concomitant with decreased fatty acid oxidation is a decrease in cellular levels of ATP until beating ceases. Midway between initiation of cultures and cessation of beating the cells begin to mobilize the stored glycogen. When the growth medium is supplemented with cortisol acetate and given to cultures which have ceased to beat, reinitiation of beating occurs. Furthermore, all decreases previously observed in ATP levels, fatty acid oxidation, and esterase activity are restored.

scholarly journals Distribution of metabolites between mitochondria and cytosol of cultured fibroblastoid rat heart cells

FEBS Letters ◽  
1979 ◽  
Vol 100 (1) ◽  
pp. 125-128 ◽  
Author(s):  
S. Soboll ◽  
K. Werdan ◽  
M. Bozsik ◽  
M. Müller ◽  
E. Erdmann ◽  
...  
Keyword(s):  
Rat Heart ◽  
Heart Cells ◽  
Rat Heart Cells
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