5168048 Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme

1993 ◽  
Vol 11 (2) ◽  
pp. 335
2004 ◽  
Vol 186 (7) ◽  
pp. 2215-2220 ◽  
Author(s):  
Beatriz Galán ◽  
José L. García ◽  
María A. Prieto

ABSTRACT The pac gene, encoding the penicillin G acylase from Escherichia coli W, is regulated by the PaaX repressor of the phenylacetate catabolic pathway. pac expression depends on the synthesis of phenylacetyl-coenzyme A. PaaX and the cyclic AMP receptor protein (CRP) bind in vitro to the Ppac promoter region. A palindromic sequence proposed as the PaaX operator is located upstream of the −35 box overlapping a CRP binding site, an unusual position that suggests a novel regulatory mechanism.


2015 ◽  
Vol 122 ◽  
pp. 240-247 ◽  
Author(s):  
Michal Grulich ◽  
Jan Brezovský ◽  
Václav ŠtĿpánek ◽  
Andrea Palyzová ◽  
Eva Kyslíková ◽  
...  

1997 ◽  
Vol 33 (9) ◽  
pp. 1481-1485 ◽  
Author(s):  
S. Skaria ◽  
E.Sreenivasa Rao ◽  
S. Ponrathnam ◽  
K.K. Kumar ◽  
J.G. Shewale

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