scholarly journals Regional left ventricular mechanical function during isometric exercise in patients with coronary artery disease: Correlation with regional coronary blood flow changes

1988 ◽  
Vol 12 (5) ◽  
pp. 1215-1221 ◽  
Author(s):  
Nicola Ferrara ◽  
Carlo Vigorito ◽  
Dario Leosco ◽  
Arturo Giordano ◽  
Pasquale Abete ◽  
...  
Author(s):  
Soroush Nobari ◽  
Rosaire Mongrain ◽  
Richard Leask ◽  
Raymond Cartier

Coronary artery disease (CAD) is considered to be a major cause of mortality and morbidity in the developing world. It has recently been shown that aortic root pathologies such as aortic stiffening and calcific aortic stenosis can contribute to the initiation and progression of this disease by affecting coronary blood flow [1,2]. Such pathologies influence the distensibility of the aortic root and therefore the hemodynamics of the entire region. As a consequence the coronary blood flow and velocity profiles will be altered [3,4,5] which could accelerate the development of an existing coronary artery disease. However, it would be very interesting to see if an occluded coronary artery would have a mutual impact on valvular dynamics and aortic root pathologies. This bi-directionality could aggravate and contribute to the progression of both the coronary and aortic root pathology.


1998 ◽  
Vol 94 (s38) ◽  
pp. 5P-5P
Author(s):  
CM Webb ◽  
JG McNeill ◽  
GMC Rosano ◽  
P Coluns

2011 ◽  
Vol 22 (4) ◽  
pp. 270-278 ◽  
Author(s):  
Øyvind Bleie ◽  
Elin Strand ◽  
Per M. Ueland ◽  
Stein E. Vollset ◽  
Helga Refsum ◽  
...  

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