IMMUNE COMPLEX DISEASE ASSOCIATED WITH VIRAL INFECTIONS

1975 ◽  
pp. 341-356 ◽  
Author(s):  
MICHAEL B.A. OLDSTONE ◽  
FRANK J. DIXON
Keyword(s):  
Immune Complex ◽  
Complex Disease ◽  
Viral Infections ◽  
Immune Complex Disease

IMMUNE COMPLEX DISEASE IN CHRONIC VIRAL INFECTIONS

1971 ◽  
Vol 134 (3) ◽  
pp. 32-40 ◽  
Author(s):  
Michael B. A. Oldstone ◽  
Frank J. Dixon
Keyword(s):  
Immune Complex ◽  
Complex Disease ◽  
Viral Infections ◽  
Immune Complex Disease ◽  
Chronic Viral Infections ◽  
Hog Cholera ◽  
B Virus ◽  
Human Disorders ◽  
Antiviral Antibody ◽  
Murine Infections

Chronic viral infections of animals associated with immune complex disease resemble a number of human disorders. At present, on the basis of showing (a) virus, host antiviral antibody, and C3 deposited in a granular pattern along the glomerular capillary wall and in the mesangia and (b) virus-host Ig (presumably antiviral antibody) complexes in the circulation, immune complex disease occurs in chronic murine infections with LCM, LDV, MSV, and ADM. In addition, granular deposits in the glomeruli in Coxsachie B, polyoma, other leukemic viral infections in mice, equine anemia, and hog cholera suggest that immune complex disease also occurs in these infections. In transplacental LCM infections maternal antiviral antibody transferred in utero or via milk induces very early and severe immune complex disease. The severity of immune complex nephritis in mice neonatally or transplacentally infected with LCM virus is directly proportional to the amount of Ig elutable from the kidney and to the proportion of this Ig which reacts with the infecting virus.

scholarly journals C1q nephropathy: a true immune complex disease or an immunologic epiphenomenon?

2009 ◽  
Vol 2 (4) ◽  
pp. 285-291
Author(s):  
M. Muorah ◽  
M. D. Sinha ◽  
C. Horsfield ◽  
P. J. O'Donnell
Keyword(s):  
Immune Complex ◽  
Complex Disease ◽  
Immune Complex Disease ◽  
C1q Nephropathy

Immunopathology of Immune Complex Disease

1983 ◽  
pp. 371-390
Author(s):  
U. E. Nydegger ◽  
M. D. Kazatchkine ◽  
P. H. Lambert ◽  
P. A. Miescher
Keyword(s):  
Immune Complex ◽  
Complex Disease ◽  
Immune Complex Disease
Sign in / Sign up

Export Citation Format

Share Document