Matrix metalloproteinases and their inhibitors in the cervical mucus plug at term of pregnancy

2004 ◽  
Vol 191 (4) ◽  
pp. 1232-1239 ◽  
Author(s):  
Naja Becher ◽  
Merete Hein ◽  
Carl Christian Danielsen ◽  
Niels Uldbjerg
Keyword(s):  
Matrix Metalloproteinases ◽  
Cervical Mucus ◽  
Mucus Plug

scholarly journals The Cervicovaginal Mucus Barrier

2020 ◽  
Vol 21 (21) ◽  
pp. 8266
Author(s):  
Guillaume Lacroix ◽  
Valérie Gouyer ◽  
Frédéric Gottrand ◽  
Jean-Luc Desseyn
Keyword(s):  
Bacterial Vaginosis ◽  
Preterm Delivery ◽  
Physiological State ◽  
Preterm Births ◽  
Cervical Mucus ◽  
Cervical Canal ◽  
Current State ◽  
Mucus Plug ◽  
Mucus Barrier ◽  
Cervicovaginal Mucus

Preterm births are a global health priority that affects 15 million babies every year worldwide. There are no effective prognostic and therapeutic strategies relating to preterm delivery, but uterine infections appear to be a major cause. The vaginal epithelium is covered by the cervicovaginal mucus, which is essential to health because of its direct involvement in reproduction and functions as a selective barrier by sheltering the beneficial lactobacilli while helping to clear pathogens. During pregnancy, the cervical canal is sealed with a cervical mucus plug that prevents the vaginal flora from ascending toward the uterine compartment, which protects the fetus from pathogens. Abnormalities of the cervical mucus plug and bacterial vaginosis are associated with a higher risk of preterm delivery. This review addresses the current understanding of the cervicovaginal mucus and the cervical mucus plug and their interactions with the microbial communities in both the physiological state and bacterial vaginosis, with a focus on gel-forming mucins. We also review the current state of knowledge of gel-forming mucins contained in mouse cervicovaginal mucus and the mouse models used to study bacterial vaginosis.

scholarly journals Protein profiling underscores immunological functions of uterine cervical mucus plug in human pregnancy

2011 ◽  
Vol 74 (6) ◽  
pp. 817-828 ◽  
Author(s):  
Deug-Chan Lee ◽  
Sonia S. Hassan ◽  
Roberto Romero ◽  
Adi L. Tarca ◽  
Gaurav Bhatti ◽  
...  
Keyword(s):  
Cervical Mucus ◽  
Protein Profiling ◽  
Human Pregnancy ◽  
Mucus Plug

scholarly journals Trefoil factor peptide 3 is positively correlated with the viscoelastic properties of the cervical mucus plug

2016 ◽  
Vol 96 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Sara K. Bastholm ◽  
Mie H. Samson ◽  
Naja Becher ◽  
Lea K. Hansen ◽  
Peter R. Stubbe ◽  
...  
Keyword(s):  
Viscoelastic Properties ◽  
Cervical Mucus ◽  
Trefoil Factor ◽  
Mucus Plug

Immunoglobulin levels and phagocytes in the cervical mucus plug at term of pregnancy

2005 ◽  
Vol 84 (8) ◽  
pp. 734-742 ◽  
Author(s):  
Merete Hein ◽  
Astrid C. Petersen ◽  
Rikke Bek Helmig ◽  
Niels Uldbjerg ◽  
Jesper Reinholdt
Keyword(s):  
Cervical Mucus ◽  
Mucus Plug ◽  
Immunoglobulin Levels

The viscoelastic properties of the cervical mucus plug

2014 ◽  
Vol 93 (2) ◽  
pp. 201-208 ◽  
Author(s):  
Sara K. Bastholm ◽  
Naja Becher ◽  
Peter R. Stubbe ◽  
Ioannis S. Chronakis ◽  
Niels Uldbjerg
Keyword(s):  
Viscoelastic Properties ◽  
Cervical Mucus ◽  
Mucus Plug

Antimicrobial factors in the cervical mucus plug

2002 ◽  
Vol 187 (1) ◽  
pp. 137-144 ◽  
Author(s):  
Merete Hein ◽  
Erika V. Valore ◽  
Rikke Bek Helmig ◽  
Niels Uldbjerg ◽  
Tomas Ganz
Keyword(s):  
Cervical Mucus ◽  
Mucus Plug
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