OP-033 Platelet-to-Lymphocyte Ratio is Associated with No-reflow Phenomenon after Primer Percutaneous Coronary Intervention in Patients with ST-segment Elevation Myocardial Infarction

2015 ◽  
Vol 115 ◽  
pp. S14-S15
Author(s):  
Bora Demircelik ◽  
Muhammed Kemal Kahyalar ◽  
Meltem Altinsoy ◽  
Mahmut Gunesd ◽  
Fadime Bozduman ◽  
...  
Angiology ◽  
2017 ◽  
Vol 69 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Xi-peng Sun ◽  
Jing Li ◽  
Wei-wei Zhu ◽  
Dong-bao Li ◽  
Hui Chen ◽  
...  

We investigated the relationship between platelet to lymphocyte ratio (PLR) and contrast-induced nephropathy (CIN) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). We enrolled 5719 patients in 3 tertiary hospitals from January 2005 to December 2010. The PLR was calculated as the ratio of platelet to lymphocyte counts on admission. Serum creatinine level was measured before and within 72 hours after contrast medium administration. To evaluate the relation between PLR and CIN, the 5719 patients were divided into a CIN group and a non-CIN group. Contrast-induced nephropathy occurred in 252 (4.4%) patients. Patients in the CIN group had significantly higher PLR than those in the non-CIN group (173.8 [62.3] and 116.2 [51.7], respectively; P < .001). In logistic regression analysis, PLR was an independent predictor of CIN (odds ratio: 1.432, 95% confidence interval: 1.205-1.816, P = .031), along with age, diabetes mellitus, creatinine, estimated glomerular filtration rate, and neutrophil to lymphocyte ratio. In conclusion, a higher PLR was an independent risk factor for the development of CIN in patients with STEMI undergoing pPCI.


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