Aggressive B cell lymphomas in the 2017 revised WHO classification of tumors of hematopoietic and lymphoid tissues

2019 ◽  
Vol 38 ◽  
pp. 6-10 ◽  
Author(s):  
Kate E. Grimm ◽  
Dennis P. O'Malley
Keyword(s):  
B Cell ◽  
Who Classification ◽  
Lymphoid Tissues ◽  
B Cell Lymphomas ◽  
Classification Of Tumors

scholarly journals Commentary on the WHO classification of tumors of lymphoid tissues (2008): aggressive B-cell lymphomas

2009 ◽  
Vol 2 (2) ◽  
pp. 83-87 ◽  
Author(s):  
Olga Balague Ponz ◽  
German Ott ◽  
Robert P. Hasserjian ◽  
Kojo S. J. Elenitoba-Johnson ◽  
Laurence de Leval ◽  
...  
Keyword(s):  
B Cell ◽  
Who Classification ◽  
Lymphoid Tissues ◽  
B Cell Lymphomas ◽  
Classification Of Tumors

scholarly journals Commentary on the WHO classification of tumors of lymphoid tissues (2008): indolent B cell lymphomas

2009 ◽  
Vol 2 (2) ◽  
pp. 77-81 ◽  
Author(s):  
German Ott ◽  
Olga Balague-Ponz ◽  
Laurence de Leval ◽  
Daphne de Jong ◽  
Robert P. Hasserjian ◽  
...  
Keyword(s):  
B Cell ◽  
Who Classification ◽  
Lymphoid Tissues ◽  
B Cell Lymphomas ◽  
Classification Of Tumors

WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues

2019 ◽  
pp. 501-505
Author(s):  
Julie Bruneau ◽  
Thierry J. Molina
Keyword(s):  
Who Classification ◽  
Lymphoid Tissues ◽  
Classification Of Tumors

scholarly journals A Practical Approach to Diagnosis of B-Cell Lymphomas With Diffuse Large Cell Morphology

2020 ◽  
Vol 144 (2) ◽  
pp. 160-167
Author(s):  
Joy F. King ◽  
John T. Lam
Keyword(s):  
B Cell ◽  
B Cell Lymphoma ◽  
Large Cell ◽  
World Health ◽  
Lymphoid Tissues ◽  
Community Practice ◽  
B Cell Lymphomas ◽  
General Pathology ◽  
Large B Cell

Context.— Large B-cell lymphomas represent the most common non-Hodgkin lymphomas and often present as extranodal masses with advanced stage similar to metastatic tumors. Without proper intraoperative, microscopic, immunophenotypic, and cytogenetic evaluation they may be mistaken for other hematopoietic or even nonhematopoietic tumors. Also, diffuse large B-cell lymphomas often have clinical, morphologic, immunophenotypic, and cytogenetic clinical features that are similar to those of other less common B-cell lymphomas. Furthermore, classification of these neoplasms is continually becoming more refined. Objective.— To provide a rational, methodic approach to the evaluation of large B-cell lymphomas for community practice pathologists who provide general pathology services. Data Sources.— This review incorporates guidelines detailed in the 2017 update to the World Health Organization's Classification of Tumours of Haematopoietic and Lymphoid Tissues in addition to other recent peer-reviewed publications. Conclusions.— Many large B-cell neoplasms respond favorably to current treatments, but these cases also require accurate and timely diagnoses. We propose a process following a brief checklist that focuses on diffuse large B-cell lymphoma, the most common entity, and rules out other similar lymphomas in a stepwise fashion.

scholarly journals Grey Zone Lymphomas: Lymphomas with Intermediate Features

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Sylvia Hoeller ◽  
Christiane Copie-Bergman
Keyword(s):  
B Cell ◽  
Who Classification ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
World Health ◽  
Grey Zone ◽  
B Cell Lymphomas ◽  
Large B Cell Lymphoma ◽  
Large B Cell

The current classification of lymphoid neoplasms is based on clinical information, morphology, immunophenotype, and molecular genetic characteristics. Despite technical and scientific progress, some aggressive B-cell lymphomas with features overlapping between two different types of lymphomas remain difficult to classify. The updated 2008 World Health Organization (WHO) classification of Tumours of the Hematopoietic and Lymphoid Tissues has addressed this problem by creation of two new provisional categories of B-cell lymphomas, unclassifiable; one with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma and the second with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. We review here the diagnostic criteria of these two provisional entities and discuss new scientific findings in light of the 2008 WHO classification.

Revised WHO classification of tumors of hematopoietic and lymphoid tissues, 2017 (4th edition):lymphoid tumors

2019 ◽  
Vol 81 (3) ◽  
pp. 59 ◽  
Author(s):  
I. L. Polyatskin ◽  
A. S. Artemyeva ◽  
Yu. A. Krivolapov
Keyword(s):  
Who Classification ◽  
Lymphoid Tissues ◽  
Classification Of Tumors

scholarly journals Pathobiology of ALK-negative anaplastic large cell lymphoma

2011 ◽  
Vol 3 (2s) ◽  
pp. 5 ◽  
Author(s):  
Stefano A. Pileri ◽  
Claudio Agostinelli ◽  
Francesco Bacci ◽  
Elena Sabattini ◽  
Carlo Sagramoso ◽  
...  
Keyword(s):  
Anaplastic Large Cell Lymphoma ◽  
Clinical Characteristics ◽  
Who Classification ◽  
Cell Lymphoma ◽  
Large Cell ◽  
Lymphoid Tissues ◽  
Histological Findings ◽  
Classification Of Tumors ◽  
Large Cell Lymphoma

The authors revise the concept of ALK-negative anaplastic large cell lymphoma (ALCL) in the light of the recently updated WHO classification of Tumors of Hematopoietic and Lymphoid Tissues both on biological and clinical grounds. The main histological findings are illustrated as well as the phenotypic, molecular and clinical characteristics. Finally, the biological rationale for possible innovative targeted therapies is presented.

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