Saphenous Vein versus Arterial Graft to the Right System in Left-sided Arterial Revascularization

Author(s):  
Yanai Ben-Gal ◽  
Amit Gordon ◽  
Nadav Teich ◽  
Orr Sela ◽  
Amir Kramer ◽  
...  
1995 ◽  
Vol 34 (3) ◽  
pp. 227-230
Author(s):  
Hideki Hashimoto ◽  
Takaaki Isshiki ◽  
Yuji Ikari ◽  
Kazuhiro Hara ◽  
Fumihiko Saeki ◽  
...  

Author(s):  
Ipek Duman ◽  
Ömer Tanyeli ◽  
Yuksel Dereli ◽  
Pembe Oltulu ◽  
Hatice Toy ◽  
...  

IntroductionAutologous saphenous vein (SV) and internal mammary artery (IMA) are used as bypass conduits during coronary artery bypass graft surgery. Vasospasm of the arterial and venous grafts may constitute a significant clinical problem. Pretreatment with a vasodilator drug of the graft ex vivo or intraluminal injection before implantation may be used for spasm prophylaxis. This in-vitro study was designed to assess the vasoactive effects and time-dependent changes of botulinum toxin A (BTX-A) and papaverine pretreatment on vasospasm of human SV and IMA grafts. Also histomorphology of the vessels were assessed.Material and methodsSV and IMA segments were suspended in organ baths and isometric contraction responses to two different concentrationsof 5-hydroxytryptamine (5-HT) and endothelin-1 (ET-1) were recorded after incubation with two different concentrations of BTX-A and papaverine at two time points (0 hours and 2nd hour).ResultsThe results suggest that; 1) incubation with BTX-A and papaverine relaxes both SV and IMA rings contracted with 5-HT and ET-1, 2) duration of the relaxant effect of BTX-A lasts longer than papaverine, 3) no apparent histomorphologic changes are observed in the grafts under light microscopy.ConclusionsThis study demonstrates that in human SV and IMA grafts, pretreatment with both BTX-A and papaverine are safe and have a potent inhibitory effect depending on the vessel and vasoconstrictor agent. Long lasting vasodilatory effect of BTX-A on vascular smooth muscle may provide promising results for preventing venous and arterial graft spasm.


Author(s):  
Francesco Evangelista Botelho ◽  
Tarcizo Afonso Nunes ◽  
Túlio Pinho Navarro ◽  
Bruno Lima de Castro ◽  
Daniel Lopes Pinheiro ◽  
...  

ASVIDE ◽  
2018 ◽  
Vol 5 ◽  
pp. 786-786
Author(s):  
Takamichi Inoue ◽  
Tadashi Kitamura ◽  
Shinzo Torii ◽  
Kagami Miyaji

2015 ◽  
Vol 48 (6) ◽  
pp. 887-892
Author(s):  
M. Uehara ◽  
N. Takagi ◽  
S. Muraki ◽  
Y. Yanase ◽  
M. Tabuchi ◽  
...  

2014 ◽  
Vol 30 (10) ◽  
pp. 729-735 ◽  
Author(s):  
L Jones ◽  
K Parsi

Ultrasound guided sclerotherapy may be complicated by intra-arterial injections resulting in significant tissue necrosis. Here, we present a 69-year-old man with a history of right small saphenous vein “stripping”, presenting for the treatment of symptomatic lower limb varicose veins. Duplex ultrasound of the right lower limb outlined the pathway of venous incompetence. Despite the history of “stripping”, the small saphenous vein was present but the sapheno-popliteal junction was ligated at the level of the knee crease. No other unusual findings were reported at the time. During ultrasound guided sclerotherapy, subcutaneous vessels of the right posterior calf were noted to be pulsatile on B-mode ultrasound. Treatment was interrupted. Subsequent angiography and sonography showed absence of the right distal popliteal artery. A cluster of subcutaneous vessels of the right medial and posterior calf were found to be arterial collaterals masquerading as varicose veins. Injection sclerotherapy of these vessels would have resulted in significant tissue loss. This case highlights the importance of vigilance at the time of treatment and the invaluable role of ultrasound in guiding endovenous interventions.


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