scholarly journals Zeaxanthin from Porphyridium purpureum induces apoptosis in human melanoma cells expressing the oncogenic BRAF V600E mutation and sensitizes them to the BRAF inhibitor vemurafenib

2018 ◽  
Vol 28 (4) ◽  
pp. 457-467 ◽  
Author(s):  
Camille Juin ◽  
Raimundo Gonçalves de Oliveira Junior ◽  
Audrey Fleury ◽  
Chloé Oudinet ◽  
Lior Pytowski ◽  
...  
Keyword(s):  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Porphyridium Purpureum ◽  
Human Melanoma Cells

Targeting CPT1A enhances metabolic therapy in human melanoma cells with the BRAF V600E mutation

2016 ◽  
Vol 81 ◽  
pp. 76-81 ◽  
Author(s):  
Gi-Jun Sung ◽  
Hyo-Kyoung Choi ◽  
Sungmin Kwak ◽  
Ji-Hye Song ◽  
Hyeonseok Ko ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
Human Melanoma ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Metabolic Therapy ◽  
Human Melanoma Cells

scholarly journals The BRAF Inhibitor Vemurafenib Activates Mitochondrial Metabolism and Inhibits Hyperpolarized Pyruvate–Lactate Exchange in BRAF-Mutant Human Melanoma Cells

2016 ◽  
Vol 15 (12) ◽  
pp. 2987-2999 ◽  
Author(s):  
Teresa Delgado-Goni ◽  
Maria Falck Miniotis ◽  
Slawomir Wantuch ◽  
Harold G. Parkes ◽  
Richard Marais ◽  
...  
Keyword(s):  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Mitochondrial Metabolism ◽  
Human Melanoma Cells ◽  
Lactate Exchange ◽  
Braf Mutant

scholarly journals Cell surface CD63 increased by up‐regulated polylactosamine modification sensitizes human melanoma cells to the BRAF inhibitor PLX4032

2018 ◽  
Vol 33 (3) ◽  
pp. 3851-3869 ◽  
Author(s):  
Kohya Kudo ◽  
Atsuko Yoneda ◽  
Daiki Sakiyama ◽  
Kai Kojima ◽  
Takeki Miyaji ◽  
...  
Keyword(s):  
Cell Surface ◽  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Human Melanoma Cells

Abstract 4735: Constitutively active RAS and MEK confer resistance to PLX4032 in BRAF-V600E human melanoma cells

2011 ◽  
Author(s):  
Tiffany J. Somers-Edgar ◽  
Petranel Ferrao ◽  
Jason Callahan ◽  
Gideon Bollag ◽  
Rod Hicks ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
Human Melanoma ◽  
Braf V600e ◽  
Human Melanoma Cells ◽  
Constitutively Active
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