DrugBank screening revealed alitretinoin and bexarotene as liver X receptor modulators

2017 ◽  
Vol 27 (5) ◽  
pp. 1193-1198 ◽  
Author(s):  
Pascal Heitel ◽  
Janosch Achenbach ◽  
Daniel Moser ◽  
Ewgenij Proschak ◽  
Daniel Merk
Keyword(s):  
Liver X Receptor ◽  
Receptor Modulators

Carboxylic acid based quinolines as liver X receptor modulators that have LXRβ receptor binding selectivity

2008 ◽  
Vol 18 (1) ◽  
pp. 54-59 ◽  
Author(s):  
Baihua Hu ◽  
Elaine Quinet ◽  
Rayomand Unwalla ◽  
Mike Collini ◽  
James Jetter ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Receptor Binding ◽  
Liver X Receptor ◽  
Binding Selectivity ◽  
Receptor Modulators

Further modification on phenyl acetic acid based quinolines as liver X receptor modulators

2007 ◽  
Vol 15 (10) ◽  
pp. 3321-3333 ◽  
Author(s):  
Baihua Hu ◽  
James Jetter ◽  
David Kaufman ◽  
Robert Singhaus ◽  
Ronald Bernotas ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Liver X Receptor ◽  
Phenyl Acetic Acid ◽  
Receptor Modulators

1α-Hydroxy derivatives of 7-dehydrocholesterol are selective liver X receptor modulators

2017 ◽  
Vol 172 ◽  
pp. 136-148 ◽  
Author(s):  
Kaori Endo-Umeda ◽  
Atsushi Aoyama ◽  
Masato Shimizu ◽  
Minoru Ishikawa ◽  
Yuichi Hashimoto ◽  
...  
Keyword(s):  
Liver X Receptor ◽  
Receptor Modulators ◽  
Derivatives Of

Combination of Virtual Screening and High Throughput Gene Profiling for Identification of Novel Liver X Receptor Modulators

2008 ◽  
Vol 51 (7) ◽  
pp. 2057-2061 ◽  
Author(s):  
Jie-Fei Cheng ◽  
James Zapf ◽  
Kei Takedomi ◽  
Chiaki Fukushima ◽  
Tsuyoshi Ogiku ◽  
...  
Keyword(s):  
Virtual Screening ◽  
High Throughput ◽  
Liver X Receptor ◽  
Gene Profiling ◽  
Receptor Modulators

Liver X receptor modulators: a review of recently patented compounds (2009 – 2012)

2013 ◽  
Vol 23 (10) ◽  
pp. 1317-1335 ◽  
Author(s):  
Jon Loren ◽  
Zhihong Huang ◽  
Bryan A Laffitte ◽  
Valentina Molteni
Keyword(s):  
Liver X Receptor ◽  
Receptor Modulators

Structure-Guided Design ofN-Phenyl Tertiary Amines as Transrepression-Selective Liver X Receptor Modulators with Anti-Inflammatory Activity

2008 ◽  
Vol 51 (18) ◽  
pp. 5758-5765 ◽  
Author(s):  
Esther Y. Chao ◽  
Justin A. Caravella ◽  
Mike A. Watson ◽  
Nino Campobasso ◽  
Serena Ghisletti ◽  
...  
Keyword(s):  
Liver X Receptor ◽  
Inflammatory Activity ◽  
Tertiary Amines ◽  
Anti Inflammatory ◽  
Receptor Modulators

Screening for liver X receptor modulators: Where are we and for what use?

2020 ◽  
Author(s):  
Julio Buñay ◽  
Allan Fouache ◽  
Amalia Trousson ◽  
Cyrille Joussineau ◽  
Erwan Bouchareb ◽  
...  
Keyword(s):  
Liver X Receptor ◽  
Receptor Modulators

Liver X receptor modulators: a review of recently patented compounds (2007 – 2009)

2010 ◽  
Vol 20 (4) ◽  
pp. 535-562 ◽  
Author(s):  
Xiaolin Li ◽  
Vince Yeh ◽  
Valentina Molteni
Keyword(s):  
Liver X Receptor ◽  
Receptor Modulators

Selective liver X receptor modulators (SLiMs): What use in human health?

2012 ◽  
Vol 351 (2) ◽  
pp. 129-141 ◽  
Author(s):  
Emilie Viennois ◽  
Kevin Mouzat ◽  
Julie Dufour ◽  
Laurent Morel ◽  
Jean-Marc Lobaccaro ◽  
...  
Keyword(s):  
Human Health ◽  
Liver X Receptor ◽  
Receptor Modulators
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