Design, synthesis, biological evaluation and molecular docking studies of novel 3-aryl-4-anilino-2 H -chromen-2-one derivatives targeting ERα as anti-breast cancer agents

2017 ◽  
Vol 27 (12) ◽  
pp. 2668-2673 ◽  
Author(s):  
Guoshun Luo ◽  
Mingqi Chen ◽  
Weiting Lyu ◽  
Ruheng Zhao ◽  
Qian Xu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Molecular Docking ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Molecular Docking Studies

scholarly journals Design, Synthesis, Biological Evaluation and Molecular Docking Studies of Some New Sulfonamides Possessing 1,4-Benzodioxane Nucleus

2019 ◽  
Vol 66 (2) ◽  
pp. 294-307
Author(s):  
Misbah Irshad ◽  
Muhammad Athar Abbasi ◽  
Aziz Ur-Rehman ◽  
Qamar Ali ◽  
Muhammad Aslam ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Molecular Docking Studies

Phenothiazine and amide-ornamented dihydropyridines via a molecular hybridization approach: design, synthesis, biological evaluation and molecular docking studies

2019 ◽  
Vol 43 (43) ◽  
pp. 17046-17057
Author(s):  
Ramar Sivaramakarthikeyan ◽  
Shunmugam Iniyaval ◽  
Krishnaraj Padmavathy ◽  
Hui-Shan Liew ◽  
Chin-King Looi ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Molecular Hybridization ◽  
Design Synthesis ◽  
Spectral Techniques ◽  
Molecular Docking Studies ◽  
Synthetic Strategy

A series of novel phenothiazinyldihydropyridine dicarboxamides 7a–7j was synthesized by adopting a multi-step synthetic strategy and characterized through physical and spectral techniques.

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