Sentinel node biopsy in vulvar cancer: Implications for staging

2015 ◽  
Vol 29 (6) ◽  
pp. 812-821 ◽  
Author(s):  
M.H.M. Oonk ◽  
H. Hollema ◽  
A.G.J. van der Zee
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Vulvar Cancer ◽  
Node Biopsy

Comparison of recurrence after vulvectomy and lymphadenectomy with and without sentinel node biopsy in early stage vulvar cancer

2006 ◽  
Vol 103 (3) ◽  
pp. 865-870 ◽  
Author(s):  
José M. Martínez-Palones ◽  
María A. Pérez-Benavente ◽  
Antonio Gil-Moreno ◽  
Berta Díaz-Feijoo ◽  
Isabel Roca ◽  
...  
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Vulvar Cancer ◽  
Early Stage ◽  
Node Biopsy

Comparison of Recurrence after Vulvectomy and Lymphadenectomy With and Without Sentinel Node Biopsy in Early Stage Vulvar Cancer

2007 ◽  
Vol 62 (4) ◽  
pp. 240-242 ◽  
Author(s):  
Jos?? M. Mart??nez-Palones ◽  
Mar??a A. P??rez-Benavente ◽  
Antonio Gil-Moreno ◽  
Berta D??az-Feijoo ◽  
Isabel Roca ◽  
...  
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Vulvar Cancer ◽  
Early Stage ◽  
Node Biopsy

scholarly journals Sentinel node biopsy in vulvar cancer: A critical appraisal

2017 ◽  
Vol 03 (01) ◽  
pp. 005-011
Author(s):  
Neville Hacker ◽  
Ellen Barlow
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Vulvar Cancer ◽  
False Negative ◽  
False Negative Rate ◽  
Groin Dissection ◽  
Loss Of Life ◽  
Risks And Benefits ◽  
Node Biopsy ◽  
Negative Rate

AbstractSince the incorporation of inguinal-femoral lymphadenectomy into the management of patients with vulvar cancer in the mid-20th century, there have been attempts to modify or eliminate the groin dissection to decrease the risk of lower limb lymphedema. Early attempts were significantly flawed and resulted in much unnecessary loss of life because recurrence in an undissected groin is usually fatal. The best compromise yet to decrease the risk of lymphedema is sentinel node biopsy, but accumulated evidence now suggests that the false-negative rate for this procedure, if used for lesions up to 4 cm in diameter, is between 5% and 10%. Most women, properly informed of risks and benefits, are not prepared to take a 1% risk of dying from recurrent vulvar cancer to avoid lymphedema. This is the risk involved, assuming a false-negative rate of 5% and an incidence of positive nodes of 20%. For this reason, sentinel node biopsy should not be considered to be standard practice for patients with early vulvar cancer.

Surgical management of stage I and II vulvar cancer: The role of the sentinel node biopsy. Review of literature

2001 ◽  
Vol 11 (4) ◽  
pp. 255-262 ◽  
Author(s):  
A. P. H. Makar ◽  
M. Scheistroen ◽  
D. Van Den Weyngaert ◽  
C. G. Tropé
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Surgical Management ◽  
Vulvar Cancer ◽  
Early Stage ◽  
Stage I ◽  
Review Of Literature ◽  
Early Stage Disease ◽  
Node Biopsy

Abstract.Makar APH, Scheistroen M, van den Weyngaert D, Tropé CG. Surgical management of stage I and II vulvar cancer: The role of the sentinel node biopsy. Review of literature.Recognition of the psychosexual consequences of radical vulvectomy and better understanding of the lymphatic drainage and histopathologic features of vulvar cancer have led to a more conservative surgical approach, especially in patients with early-stage disease. Every patient with early vulvar cancer should be managed individually and the risk of conservative therapy balanced against the dangers and advantages of more radical therapy. The results of the sentinel node (SN) procedure in early cancer of the vulva are encouraging, and it might be possible in the near future to avoid the morbidity of inguino-femoral lymphadenectomy. This article reviews surgical management of early vulvar cancer and the place of SN biopsy.

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