A sensitivity and specificity comparison of fine needle aspiration cytology and core needle biopsy in evaluation of suspicious breast lesions: A systematic review and meta-analysis

The Breast ◽  
2017 ◽  
Vol 31 ◽  
pp. 157-166 ◽  
Author(s):  
Mei Wang ◽  
Xiaoning He ◽  
Yaping Chang ◽  
Guangwen Sun ◽  
Lehana Thabane
2017 ◽  
Vol 4 (11) ◽  
pp. 3718
Author(s):  
Shashirekha C. A. ◽  
Rahul Singh R. ◽  
Ravikiran H. R. ◽  
Sreeramulu P. N. ◽  
Krishna Prasad

Background: Most diseases of the breast present as a palpable mass. The majority of breast lesions are not malignant, and most benign lesions do not progress to cancer; however, the accuracy of diagnosis can be increased by a combination of preoperative tests like physical examination, mammography, fine-needle aspiration cytology (FNAC), and Trucut needle biopsy (TGNB) or core needle biopsy (CNB). FNAC has grown in popularity and became the first initial used procedure after history taking and clinical examination for diagnosis of solid and cystic breast lumps. This study was designated to investigate the accuracy of FNAC in comparison to TCNB for diagnosis of breast masses, Design: Retrospective Study.Methods: In this study, 62 patients having breast lumps were studied during the period from January 2014 to January 2017 in terms of FNAC and Trucut Biopsy and were compared with tissue diagnosis. Variables like age, marital status, duration, size, menstrual status and site were analyzed using statistical analysis.Results: Out of 62 patients with breast lump, 32 were diagnosed with Benign Breast lesions, and 30 with malignant lesions. Sensitivity of FNAC and TRUCUT biopsy were 84.34% and 97.1% respectively. TRUCUT was more accurate when compared to FNAC.Conclusions: Both FNAC and Core Needle Biopsy are complimentary to each other and are useful in diagnosis of breast lesions.


2021 ◽  
pp. 1-6
Author(s):  
Priyanka Verma ◽  
Reetika Sharma ◽  
Neelam Sharma ◽  
Anchana Gulati ◽  
Anupam Parashar ◽  
...  

<b><i>Introduction:</i></b> Core-needle biopsy (CNB) is a minimally invasive procedure used in preoperative diagnosis of breast lumps. It has been seen that in few years, the CNB seems to be replacing the fine-needle aspiration cytology (FNAC), although no study had yet conclusively proved a superiority of one over the other. <b><i>Aims and Objectives:</i></b> The aim of this study was to study the cytohistological spectrum of palpable breast lesions and to evaluate the diagnostic accuracy of FNAC versus CNB for breast lesions. <b><i>Materials and Methods:</i></b> The study was a cross-sectional study conducted in the Department of Pathology and Surgery, over a period of 1 year in 152 patients. All the patients were subjected to FNAC and CNB. Cytosmears were stained with May-Grunwald Giemsa and hematoxylin and eosin was done on CNB and excision biopsy (EB) specimens. Sensitivity and specificity were calculated in percentage with 95% confidence interval with reference to CNB/surgical specimens. Kappa statistics were used to compare the level of agreement between FNAC versus CNB and CNB versus surgical specimens. <b><i>Results:</i></b> A total of 152 patients were taken for FNAC and CNB. EB was performed in only 104 patients. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of FNAC verses CNB in correlation with subsequent histopathology were found to be (93.40 vs. 94.06%), (97.50 vs. 100.00%), (99.00 vs. 100.00%), (84.78 vs. 33.33%), and (94.52 vs. 94.23%), respectively. <b><i>Conclusion:</i></b> CNB has overcome the pitfall of FNAC but CNB cannot replace FNAC but both procedures are complementary to each other.


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