Abstract
Introduction
Mitral regurgitation is often found in conjunction with aortic stenosis and the prevalence of both valvular lesions increases with age.
Purpose
The aim of this study was to evaluate mitral regurgitation, left ventricle and left atrium in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI).
Methods
A total of 31 patients (29% males) with severe aortic stenosis and moderate or severe mitral regurgitation, who underwent TAVI were included in this study. Clinical and echocardiographic characteristics were performed at baseline and in 6, 12 months observation.
Results
After TAVI, decrease of vena contracta width of mitral regurgitation (p = 0.00002, p = 0.00004), aorto-mural mitral annulus diameter (p = 0.00008, p = 0.02), increase mitral annular plane systolic excursion (p = 0.0004, p = 0.0003), left ventricular stroke volume (p = 0.0003, p = 0.0004), ejection fraction (p = 0.0004, p = 0.01) and decrease major dimension of left ventricle in three chamber view (p = 0.05, p = 0.002) was observed in patient in both time points, respectively. Additionally, we observed decrease of distance between head of papillary muscles (p = 0.003) at 6 months and decrease of left atrium indexed volume (p = 0.01) and grade of tricuspid regurgitation (p = 0.03) at 12 months follow up.
Conclusions
Patients with moderate or severe mitral regurgitation after TAVI procedure achieved significant reductions of mitral regurgitation and improvement of some parameters assessing mitral annulus, left ventricle and left atrium geometry.