Fast fully automatic skin lesions segmentation probabilistic with Parzen window

Dermatoscopic images are also increasingly used to train artificial neural networks for the future to provide fully automatic diagnostic systems capable of determining the type of pigmented skin lesion. Therefore, fractal analysis was used in this study to measure the irregularity of pigmented skin lesion surfaces. This paper presents selected results from individual stages of preliminary processing of the dermatoscopic image on pigmented skin lesion, in which fractal analysis was used and referred to the effectiveness of classification by fuzzy or statistical methods. Classification of the first unsupervised stage was performed using the method of analysis of scatter graphs and the fuzzy method using the Kohonen network. The results of the Kohonen network learning process with an input vector consisting of eight elements prove that neuronal activation requires a larger learning set with greater differentiation. For the same training conditions, the final results are at a higher level and can be classified as weaker. Statistics of factor analysis were proposed, allowing for the reduction in variables, and the directions of further studies were indicated.

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Fine Structural Alterations in Thyroid Follicular Cells (FC) and Changes in Serum Thyroxine Produced by Feeding Polychlorinated Biphenyl (PCB) to Rats

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100079929 ◽

1977 ◽

Vol 35 ◽

pp. 498-499

Author(s):

W.T. Collins ◽

Charles C. Capen ◽

Louis Kasza

Keyword(s):

Feed Efficiency ◽

Polychlorinated Biphenyl ◽

Serum Proteins ◽

Skin Lesions ◽

Hepatic Necrosis ◽

Ultrastructural Changes ◽

Lymphoid Tissues ◽

Heat Transfer Fluids ◽

Thyroid Follicular Cells ◽

Peripheral Metabolism

The widespread contamination of the environment with PCB, a compound used extensively by industry in hydraulic and heat transfer fluids as well as plasticizers and solvents in adhesives and sealants, has resulted in detectable tissue levels in a large portion of the human population, domestic animals, and wildlife. Intoxication with PCB produces severe hepatic necrosis, degeneration of lymphoid tissues and kidney, skin lesions, decreased reproductive performance, reduced feed efficiency, and decreased weight gain. PCB also has been reported to reduce the binding of thyroid hormone to serum proteins and enhance the peripheral metabolism of thyroxine with increased excretion of thyroxine-glucuronide in the bile (Bastomsky, Endocrinology 95: 1150-1155, 1974).The objectives of this investigation were (1) to investigate the histopathologic, histochemical, and ultrastructural changes in thyroid FC produced by the acute (4 week) and chronic (12 week) administration of low (50 ppm) and high (500 ppm) doses of PCB to rats, (2) to correlate these alterations to changes in serum immunoreactive thyroxine concentration, and (3) to investigate the persistence of the effects of PCB on the thyroid gland.

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A new method of complex structure analysis by electron microscopy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100110283 ◽

1978 ◽

Vol 36 (1) ◽

pp. 628-629

Author(s):

V.V. Rybin ◽

E.V. Voronina

Keyword(s):

Complex Structure ◽

Reciprocal Lattice ◽

Stacking Faults ◽

Plastic Strains ◽

Base Position ◽

Structural Regularity ◽

Orientation Matrix ◽

Computerized Processing ◽

Fully Automatic ◽

Diffraction Patterns

Recently, it has become essential to develop a helpful method of the complete crystallographic identification of fine fragmented crystals. This was maainly due to the investigation into structural regularity of large plastic strains. The method should be practicable for determining crystallographic orientation (CO) of elastically stressed micro areas of the order of several micron fractions in size and filled with λ>1010 cm-2 density dislocations or stacking faults. The method must provide the misorientation vectors of the adjacent fragments when the angle ω changes from 0 to 180° with the accuracy of 0,3°. The problem is that the actual electron diffraction patterns obtained from fine fragmented crystals are the superpositions of reflections from various fragments, though more than one or two reflections from a fragment are hardly possible. Finally, the method should afford fully automatic computerized processing of the experimental results.The proposed method meets all the above requirements. It implies the construction for a certain base position of the crystal the orientation matrix (0M) A, which gives a single intercorrelation between the coordinates of the unity vector in the reference coordinate system (RCS) and those of the same vector in the crystal reciprocal lattice base : .

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